Advanced glycation end-products (AGEs) are produced during protein glycation and associated with diabetic complications. Peanut skin is rich in procyanidins, which may be used as an inhibitor of glycation. This study evaluated the potential anti-glycation effect of peanut skin extract (PSE) and dissected the underlying mechanism. PSE could effectively inhibit the formation of AGEs in BSA-Glc and BSA-MGO/GO models, with 44%, 37% and 82% lower IC values than the positive control (AG), respectively. The inhibitory effect of PSE on BSA glycation might be ascribed to its binding interaction with BSA, attenuated formation of early glycation products and trapping of reactive dicarbonyl compounds. Notably, PSE showed a remarkably stronger inhibitory effect on Amadori products than AG. Furthermore, three new types of PSE-MGO adducts were formed as identified by UPLC-Q-TOF-MS. These findings suggest that PSE may serve as an inhibitor of glycation and provide new insights into its application.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.foodchem.2021.130169 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A case of acquired syphilis in an infant through mouth-to-mouth transmission of prechewed food.
Int J STD AIDS
January 2025
Department of Dermatology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Background: Patients with syphilis are the only source of infection, which can be transmitted through sexual contact and mother-to-child and blood transmission, and rarely through contaminants. The clinical manifestations of syphilis are complex and variable, and can be easily misdiagnosed. This article reports a case of syphilis in a child with "psoriasis"-like lesions who was fed pre-chewed food.
View Article and Find Full Text PDFAra h 2-expressing cucumber mosaic virus-like particle (VLP Peanut) induces in vitro tolerogenic cellular responses in peanut-allergic individuals.
J Allergy Clin Immunol
January 2025
National Heart and Lung Institute, Imperial College London, London, United Kingdom. Electronic address:
Background: Peanut allergy (PA) is one of the most prevalent food allergies with a lack of favorable safety/efficacy treatment. A cucumber mosaic virus-like particle expressing peanut allergen component Ara h 2 (VLP Peanut) has been developed as a novel therapeutic approach for PA.
Objective: We assessed the tolerogenic properties and reactivity of VLP Peanut.
Effects of Peanut Shell Flavonoids on Composite Film Properties and Cherry Tomato Preservation.
Food Sci Nutr
December 2024
Department of Information, College of Medicine and Biological Information Engineering Northeastern University Shenyang China.
This study investigated the effects of varying concentrations of peanut shell flavonoids (PSFs) on the properties of peanut meal extract-tilapia skin protein composite films and their impact on cherry tomatoes preservation. Peanut meal alcohol extract (Pe) and tilapia skin protein (Co) were used as base materials, combined with PSFs to prepare composite films with excellent antioxidant properties. The results demonstrated that the optimized composite films exhibited superior mechanical properties, with a tensile strength of 9.
View Article and Find Full Text PDF[Analysis of the distribution characteristics of allergen sIgE detection in patients with respiratory and skin mucosal diseases in a hospital in Shanghai City from 2022 to 2023].
Zhonghua Yu Fang Yi Xue Za Zhi
December 2024
Department of Clinical Laboratory, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai200336, China.
Article Synopsis
- - The study analyzed serum allergen-specific IgE (sIgE) in 3,822 patients with respiratory and skin diseases in Shanghai over one year to help understand and improve the diagnosis and treatment of allergies in the region.
- - Results revealed that 88.4% of patients tested positive for at least one allergen, with 72.9% exhibiting multiple allergy sensitivities; the most common allergens included house dust mites, milk, fungi, and certain tropical mites.
- - Statistical analysis indicated that certain allergens like cat dandruff were more prevalent in respiratory diseases, while food allergens like shrimp and crab showed lower positivity rates, providing insights into the allergen distribution for targeted prevention strategies.
An Improved pH-Driven Method for Upcycling Polyphenols from Plants or Byproducts into Foods.
Foods
December 2024
Department of Food Science and Technology, College of Agricultural and Environmental Sciences, University of Georgia, Griffin, GA 30223, USA.
The incorporation of polyphenols into food systems provides various health benefits, yet their stability and bioactivity are often compromised by processing conditions. In this study, we advanced the pH-driven method for processing highly pH-sensitive polyphenols, such as quercetin, by optimizing operating conditions, including minimizing oxygen exposure and reducing operating times. As a result, an improved post-pH-driven (PPD) method was developed to encapsulate pH-sensitive quercetin into nanoemulsions with an encapsulation efficiency exceeding 95%, indicating that this method could be broadly applicable for incorporating various polyphenols.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!