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Development of Bayesian segmented Poisson regression model to forecast COVID-19 dynamics based on wastewater data: a case study in Nanning City, China.
BMC Public Health
January 2025
Department of Infectious Diseases, Nanning Center for Disease Control and Prevention, Nanning, 530023, China.
Introduction: COVID-19 has caused tremendous hardships and challenges around the globe. Due to the prevalence of asymptomatic and pre-symptomatic carriers, relying solely on disease testing to screen for infections is not entirely reliable, which may affect the accuracy of predictions about the pandemic trends. This study is dedicated to developing a predictive model aimed at estimating of the dynamics of COVID-19 at an early stage based on wastewater data, to assist in establishing an effective early warning system for disease control.
View Article and Find Full Text PDFEvaluation of self-collected dried blood spots for detection of SARS-CoV-2 nucleocapsid antibodies shows low sensitivity.
J Immunol Methods
January 2025
Cantonal Hospital St. Gallen, Clinic for infectious diseases and hospital hygiene, Switzerland; Children Hospital of Eastern Switzerland; Switzerland. Electronic address:
Background And Aims: Dried blood spots (DBS) have been proposed as a cost-effective surveillance method for population-wide screening of SARS-CoV-2 immunity but sensitivity of DBS based on self-collected DBS samples is unknown. To evaluate the success of vaccination strategies, it is necessary to differentiate vaccination from natural infection. Therefore, a test for antibodies against the viral nucleocapsid protein (anti-N) is desirable.
View Article and Find Full Text PDFThe impact of telemedicine on pediatric type 1 diabetes management: benefits, challenges, and future directions.
Front Endocrinol (Lausanne)
January 2025
Università degli Studi di Milano, Milano, Italy.
Telemedicine (TM) has emerged as a valuable tool in managing pediatric type 1 diabetes (T1D), particularly during the COVID-19 pandemic when traditional in-person visits were limited. This narrative review examines the impact of TM on patient-provider relationships, glycemic control, and overall diabetes management in children and adolescents with T1D. Studies consistently demonstrate high levels of patient and provider satisfaction with TM, citing increased consultation frequency, reduced travel burdens, and lower associated costs.
View Article and Find Full Text PDFFour COVID-19 screening strategies for early case identification within the homeless shelter population: a cluster randomized controlled trial.
BMC Infect Dis
December 2024
Department of Medicine, McMaster University, Hamilton, ON, Canada.
Background: To compare the effectiveness of four surveillance strategies for detecting SARS-CoV-2 within the homeless shelter population in Hamilton, ON and assess participant adherence over time for each surveillance method.
Methods: This was an open-label, cluster-randomized controlled trial conducted in eleven homeless shelters in Hamilton, Ontario, from April 2020 to January 2021. All participants who consented to the study and participated in the surveillance were eligible for testing by self-swabbing.
Longitudinal analysis of SARS-CoV-2 IgG antibody durability in Puerto Rico.
Sci Rep
December 2024
Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.
Article Synopsis
- The study focuses on understanding how IgG antibody levels against SARS-CoV-2 behave over time in a group of people from Puerto Rico, especially in relation to vaccination and prior infections.
- Researchers conducted a longitudinal analysis with participants providing regular samples for testing from June 2020 to August 2022, allowing them to assess how antibody levels changed based on factors like vaccination status and the timing of infections.
- Findings revealed that a significant majority of participants showed increased antibody prevalence by the end of the study, with vaccinations contributing substantially to IgG levels, while a third booster dose was effective in enhancing and prolonging antibody response.
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