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http://dx.doi.org/10.1111/ans.16987 | DOI Listing |
Cureus
August 2024
Department of Obstetrics, Gynecology & Reproductive Health, Rutgers University New Jersey Medical School, Newark, USA.
JAMA Pediatr
December 2023
Department of Endocrinology and Metabolism, Amsterdam University Medical Center (UMC) at Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Importance: Bone mineral density (BMD) z scores in transgender adolescents decrease during puberty suppression with a gonadotropin-releasing hormone (GnRH) agonist. Previous research found that after short-term use of gender-affirming hormones (GAH), pretreatment z scores were not restored. Long-term follow-up studies are lacking.
View Article and Find Full Text PDFGen Comp Endocrinol
September 2023
Department of Zoology and Entomology, University of Pretoria, 0028 Pretoria, South Africa. Electronic address:
Kisspeptin, a product of the Kiss1 gene is considered a potent stimulator of gonadotropin release, by interacting with its receptor, the G protein-coupled receptor 54. Kiss1 neurons are known to mediate the positive and negative feedback effects of oestradiol on GnRH neurons that control the pulsatile and surge secretion of GnRH. While in spontaneously ovulating mammals the GnRH/LH surge is initiated by a rise in ovarian oestradiol secreted from maturing follicles, in induced ovulators, the primary trigger is the mating stimulus.
View Article and Find Full Text PDFHorm Behav
July 2023
Department of Biological Sciences, Idaho State University, Pocatello, ID 83209, United States of America.
For vertebrates living in social hierarchies, the neuroendocrine system regulates temporal aspects of aggressive interactions during status establishment. In teleost fishes, the sex steroids 17β-estradiol (E) and 11-ketotestosterone (KT), and the glucocorticoid, cortisol (CORT) are associated with aggression in distinct phases of their life history. Bluebanded gobies, Lythrypnus dalli, exhibit bidirectional sexual plasticity by responding to changes in their social structure by escalating aggression associated with neural changes that precede gonadal reorganization to the opposite sex.
View Article and Find Full Text PDFMed Oncol
February 2023
Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it mostly arises as a consequence of persistent chronic inflammation. Recently, NLRP3 inflammasome has caught the attention of many research groups due to its involvement in different types of cancer. However, its direct role in HCC remains elusive.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!