Background: According to United Nations Office on Drugs and Crime (UNODC) around 243 million people, aged 15-64 consumed an illicit substance making this a public health problem of global dimensions with attendant physical, social, and psychological problems. Studies have shown that 59.5% of road traffic accident among commercial tricycle operator has been associated with the use of psychoactive substances. Hence, this study was conducted to assess the prevalence and pattern of psychoactive substance use and its predictors among tricycle operators in Jos north local government area of Plateau State.
Methodology: This was a cross sectional study conducted among 220 commercial tricycle operators selected from a cluster of five operational units of Tricycle Riders Union using quantitative data collection instrument consisted of three sections through an interviewer's administration method.
Results: The mean age of the respondents in the study was 34 ± 10 years with the prevalence of current use of psychoactive substance being 43.2%. The predictors of psychoactive substance use were tertiary level of education (AOR = 0.06; 95% CI = 0.0074-0.4806) and family history of use of psychoactive substance (AOR = 3.30; 95% CI = 1.7164-6.3611).
Conclusion: This study has demonstrated a high level of illicit psychoactive substance use among commercial tricycle operators with higher level of education negatively influence its use and a positive family history potentiating it.
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http://dx.doi.org/10.4103/jomt.jomt_44_19 | DOI Listing |
PLoS One
January 2025
Department of Disease Control and Environmental Health, School of Public Health, Makerere University, Kampala, Uganda.
Background: Psychoactive substance use in adults and second-hand smoke (SHS) exposure among children are leading contributors to sleeping problems. Despite this, there is limited data on how these exposures influence sleep patterns in informal settings. Our study assessed the associations between substance use, SHS exposure and sleep disturbances among adults and children in an urban informal settlement in Uganda.
View Article and Find Full Text PDFArch Toxicol
January 2025
School of Chemistry and Chemical Engineering, Guangxi University, Nanning, Guangxi, 530004, People's Republic of China.
Over the past decade, fentanyl-type new psychoactive substances (F-NPS) have emerged as the most representative synthetic opioids in third-generation drugs. These substances are characterized by their "low" fatal dose and parent drug levels in biological matrices, "fast" rates of derivatization and metabolism, and "many" derivatization sites and analogs. The low levels of parent fentanyl NPS in biological matrices complicate their detection, necessitating the use of characteristic metabolites as biomarkers for forensic analysis.
View Article and Find Full Text PDFTunis Med
December 2024
Pneumology Department, Gabès University Hospital, Faculty of Medicine of Sfax, Gabès, Tunisia.
Introduction: Information on the use of tobacco and other illicit substances by young people is an essential element for the implementation of appropriate preventive measures.
Aim: To estimate the prevalence of smoking, alcohol and drug use among high school students in the city of Gabes.
Methods: Cross-sectional survey carried out in 2022 in 5 schools in the city of Gabes, southern Tunisia, by a self-administered questionnaire.
J Psychoactive Drugs
January 2025
Child and Adolescent Psychiatry, Department of Clinical Sciences, Lund University, Lund, Sweden.
In the midst of growing research and societal discourse on psychedelic substances, a consistent finding is reported: A majority of users report profound personal meaning from their experiences. This pioneering study in Sweden, a nation renowned for its strict drug policies, sought to quantify the extent of reported meaningfulness among Swedish psychedelic users. Results revealed that a majority of the sample, 58%, ranked their psychedelic experience among the top 5 most meaningful events in their lives, while 85% among the top 10.
View Article and Find Full Text PDFPsychopharmacol Bull
January 2025
Sychev, corresponding member of the Academy of Sciences of Russia, MD, PhD, MD, professor, rector, head of clinical pharmacology and therapy department, Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Moscow, Russian Federation.
Introduction: Alcoholic hallucinosis (AH) is one of the severe complications of chronic alcoholism, characterized by psychotic symptoms such as auditory hallucinations and delusions. Haloperidol is widely used to treat AH; however, its therapy is often complicated by side effects. A personalized approach using pharmacogenetic testing (particularly the CYP2D6 polymorphism) allows individualization of haloperidol dosage, improving both safety and efficacy of therapy.
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