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Population-level impact of COVID-19 on thyroid function tests: Results from a repeated cross-sectional study.

J Infect Public Health

January 2025

Department of Genomic Medicine, Division of Biochemistry, Molecular Biology, and Nutrition, University Hospital of Nancy, Nancy F-54000, France; Reference Center for Inborn Errors of Metabolism (ORPHA67872), University Hospital of Nancy, Nancy F-54000, France; Faculty of Medicine of Nancy, University of Lorraine, Nancy F-54000, France; INSERM UMR_S 1256, Nutrition, Genetics, and Environmental Risk Exposure (NGERE), Nancy F-54000, France. Electronic address:

Purpose: Reports have highlighted thyroid abnormalities, including subacute thyroiditis and thyrotoxicosis, in COVID-19 patients, with a potential link between thyroid dysfunction and disease severity. However, population-level studies on COVID-19's impact on thyroid hormone levels are limited. We aimed to assess the impact of the COVID-19 pandemic on thyroid function tests at the population level.

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Incidence and Risk Factors for Amiodarone-Induced Thyroid Dysfunction: A Nationwide Retrospective Cohort Study.

Am J Cardiovasc Drugs

January 2025

Division of Cardiology, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea.

Background: Amiodarone is an effective anti-arrhythmic drug; however, it is frequently associated with thyroid dysfunction. The aim of this study was to investigate the incidence and risk factor of amiodarone-induced dysfunction in an iodine-sufficient area.

Methods: This retrospective cohort study included 27,023 consecutive patients treated with amiodarone for arrhythmia, using the Korean National Health Insurance database.

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Article Synopsis
  • A case study discusses primary hypogonadism caused by prolonged use of amiodarone, a medication known for multiple side effects.
  • The patient, a 57-year-old man, experienced testicular pain, gynaecomastia, and decreased libido, ultimately diagnosed with hypergonadotropic hypogonadism and confirmed testicular atrophy.
  • The findings emphasize the need for careful monitoring of patients on amiodarone to detect signs of testicular dysfunction early, ensuring appropriate treatment for hypogonadism.
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Introduction: Thyroid disorders are a common manifestation of hormonal disorders that result from either excessive or insufficient production of thyroid hormones and the swelling of the thyroid gland. A lack of information and awareness of the signs and risk factors of thyroid problems can lead to untreated patients, thereby harming public health.

Methods: Observational cross-sectional research was conducted in the Al-Baha region of Saudi Arabia, with 531 residents selected from the general population.

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Iodine and Hyperthyroidism: A Double-Edged Sword.

Endocr Pract

November 2024

Section of Endocrinology, Diabetes, Nutrition, and Weight Management, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts. Electronic address:

Objective: This article serves as an update to a 1995 review by Braverman and Roti that was publishsed in the inaugural issue of Endocrine Practice.

Methods: We searched PubMed for relevant English-language literature and identified additional papers cited in recent reviews.

Results: Iodine is a trace element found in the Earth's crust that is necessary for the biosynthesis of thyroid hormones.

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