This study reviews the extent to which Universal Design of digitalized work tools is not only a useful, but a necessary principle to support inclusion in an ageing workforce. But Universal Design must be understood and implemented in a broader sense than "classic" adaptation. It includes areas like services, digitalization training and user interface between mainstream and assistive technologies. It makes requirements to an enterprise's management system and training policy, besides mainstream human resources policies. The paper goes through these requirements and concludes with the need to improve our understanding of the principle of Universal Design for it to be an efficient tool for inclusive workplaces: not only the digital work tools have to be accessible, but it must be combined with management policy, training and support.
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http://dx.doi.org/10.3233/SHTI210416 | DOI Listing |
Lab Chip
January 2025
NASCENT Engineering Research Center, The University of Texas at Austin, Austin, Texas 78758, USA.
Despite being a high-resolution separation technique, deterministic lateral displacement (DLD) technology is facing multiple challenges with regard to design, manufacture, and operation of pertinent devices. This work specifically aims at alleviating difficulties associated with design and manufacture of DLD chips. The process of design and production of computer-aided design (CAD) mask layout files that are typically required for computational modeling analysis, optimization, as well as for manufacturing DLD-based micro/nanofluidic chips is complex, time-consuming, and often necessitates a high level of expertise in the field.
View Article and Find Full Text PDFInt J Nurs Stud Adv
June 2025
Los Angeles General Medical Center, Los Angeles, CA, United States.
Background: There is a lack of high-quality evidence to support the recommendation of an instrument to screen emergency department patients for their risk for violence.
Objective: To demonstrate the content and predictive validity and reliability of the novel Risk for Violence Screening Tool to identify patients at risk for violence.
Design And Setting: This retrospective risk screening study was conducted at a 100-bed emergency department in an urban, academic, safety net trauma center in Southern California.
Child Adolesc Ment Health
January 2025
Assessment and Evaluation Research Centre, Faculty of Education, University of Melbourne, Melbourne, Vic., Australia.
Universal school-based mental health interventions present a promising approach to addressing youth mental health challenges; however, evidence suggests their effectiveness is often limited and unsustained. One contributing factor to this issue is the frequent superficial involvement of students in the design, implementation and evaluation of initiatives. In response, this paper advocates for the urgent prioritisation of student voice within these programmes, using in-depth and purposive qualitative approaches that empower youth to actively co-create and shape interventions.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
SKKU Advanced Institute of Nanotechnology (SAINT), Department of Nano Engineering, Department of Nano Science and Technology, School of Chemical Engineering, Biomedical Institute for Convergence at SKKU, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 16419, Republic of Korea.
Despite their safety and widespread use, conventional protein antigen-based subunit vaccines face significant challenges such as low immunogenicity, insufficient long-term immunity, poor CD8 T-cell activation, and poor adaptation to viral variants. To address these issues, an infection-mimicking gel (IM-Gel) is developed that is designed to emulate the spatiotemporal dynamics of immune stimulation in acute viral infections through in situ supramolecular self-assembly of nanoparticulate-TLR7/8a (NP-TLR7/8a) and an antigen with tannic acid (TA). Through collagen-binding properties of TA, the IM-Gel enables sustained delivery and enhanced retention of NP-TLR7/8a and protein antigen in the lymph node subcapsular sinus of mice for over 7 days, prolonging the exposure of vaccine components in both B cell and T cell zones, leading to robust humoral and cellular responses.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
City of Hope National Medical Center, Duarte, California.
Importance: Enhanced breast cancer screening with magnetic resonance imaging (MRI) is recommended to women with elevated risk of breast cancer, yet uptake of screening remains unclear after genetic testing.
Objective: To evaluate uptake of MRI after genetic results disclosure and counseling.
Design, Setting, And Participants: This multicenter cohort study was conducted at the University of Southern California Norris Cancer Hospital, the Los Angeles General Medical Center, and the Stanford University Cancer Institute.
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