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Management and disease burden of children and adults with severe IgE-mediated food allergy: Are adults the lost population?
World Allergy Organ J
December 2024
Novartis Pharma GmbH, Nuernberg, Germany.
Background: Lacking causal treatment options in most cases, severe IgE-mediated food allergies (IgE-FA) are associated with a high burden of disease due to permanent risk of anaphylactic reactions after accidental allergen ingestion. To date, only few data comparing health resources and burden of disease between the pediatric and adult population are available.
Objective: Our survey aimed to assess the care situation of pediatric and adult patients with severe, self-reported physician-diagnosed IgE-FA.
Primary prevention of food allergy: beyond early introduction.
Allergy Asthma Clin Immunol
December 2024
Department of Pediatrics, Division of Allergy, Dalhousie University, IWK Health Centre, Halifax, NS, Canada.
Food allergy typically begins early in life and persists as a lifelong condition. Delayed introduction of allergenic foods followed by years of hesitancy to introduce these foods early may have contributed to the increase in food allergy prevalence in recent decades. Most infant feeding guidelines focus on the importance of early introduction of allergenic foods in infants at around age 4-6 months.
View Article and Find Full Text PDFTreatment of food allergy: Immunotherapy, omalizumab, or both.
J Allergy Clin Immunol Pract
December 2024
Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, California, USA. Electronic address:
Food allergy is a common disease which has substantial impacts on the quality of life of patients and their families, and all reactions have the potential for causing life-threatening anaphylaxis. Food allergic individuals currently have 2 FDA approved therapeutic options available to them aside from life-long allergen avoidance: oral immunotherapy (OIT), and omalizumab. OIT for food allergy has been extensively studied in clinical trials and currently provides the greatest level of protection, however it also has a high burden of treatment.
View Article and Find Full Text PDFConflicting predictions of whole egg versus egg component testing: A case report.
J Allergy Clin Immunol Glob
February 2025
Ochsner Health System, New Orleans, La.
The results of component testing for patients with egg allergy may conflict with the results of whole allergen testing, with the potential of influencing patients' decision to undergo high-risk ingestion challenge.
View Article and Find Full Text PDFOccupational anaphylaxis: A Position Paper of the German Society of Allergology and Clinical Immunology (DGAKI).
Allergol Select
November 2024
Department of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich TUM).
Background: Anaphylaxis is a systemic allergic reaction that is potentially life-threatening. Occupational anaphylaxis is an anaphylaxis that occurs in an occupational context. In this position paper, we propose diagnostic criteria for occupational anaphylaxis and provide an overview of the current state of knowledge in terms of prevalence, triggers, prevention, and management.
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