Monitoring excited-state relaxation in a molecular marker in live cells-a case study on astaxanthin.

Chem Commun (Camb)

Leibniz Institute of Photonic Technology (Leibniz-IPHT), Albert-Einstein-Strabe 9, Jena 07745, Germany. and Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, Jena 07743, Germany.

Published: June 2021

AI Article Synopsis

  • Small molecules, like dyes and labels, help visualize and study processes inside cells, but their behavior under light hasn't been well researched.
  • This study focuses on the excited-state dynamics of astaxanthin, a well-known molecular marker, within live human cells.
  • An experimental method is introduced to analyze how this marker reacts when exposed to light on a picosecond (ps) timescale.

Article Abstract

Small molecules are frequently used as dyes, labels and markers to visualize and probe biophysical processes within cells. However, very little is generally known about the light-driven excited-state reactivity of such systems when placed in cells. Here an experimental approach to study ps time-resolved excited state dynamics of a benchmark molecular marker, astaxanthin, in live human cells is introduced.

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Source
http://dx.doi.org/10.1039/d1cc01907dDOI Listing

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