Despite entailing more severe and uncommon side effects in 22q11.2DS compared to idiopathic schizophrenia, we strongly believe that clozapine should continue to be considered the gold standard for all treatment-resistant schizophrenia, even in 22qDS.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142464PMC
http://dx.doi.org/10.1002/ccr3.4134DOI Listing

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