AI Article Synopsis
- The clear-cell variant of oral squamous cell carcinoma is very rare in the mouth and jaw area, and this report details a case of a 42-year-old female with a soft tissue growth on her alveolar mucosa.
- The growth had irregular white patches and was present for three months, leading to a histopathologic examination that revealed malignant clear cells.
- Immunohistochemical studies confirmed the presence of these cells while showing negativity for other common markers, helping to identify the cancer's characteristics.
Article Abstract
Clear-cell variant of oral squamous cell carcinoma is an extremely rare entity in the maxillofacial region. We report a case of 42-year-old female who presented with a soft-tissue growth with erythematous and nonscrapable irregular white patches on the left alveolar mucosa for the past 3 months. Histopathologic examination showed lobules and sheets of clear cells with features of malignancy extending from the surface epithelium. Periodic acid-Schiff and mucicarmine stains showed a negative reaction. Immunohistochemical study using antibody for pan-cytokeratin revealed intense positivity and negative for the markers such as S-100, smooth muscle actin and CD 117.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123239 | PMC |
| http://dx.doi.org/10.4103/jomfp.JOMFP_295_20 | DOI Listing |
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