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| http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_73_20 | DOI Listing |
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Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
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Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland.
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Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.
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Structural alterations of thalamic nuclei and their associations with leptin levels in patients with anorexia nervosa.
Prog Neuropsychopharmacol Biol Psychiatry
January 2025
Translational Developmental Neuroscience Section, Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, TU Dresden, Dresden, Germany; Eating Disorder Treatment and Research Center, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Dresden, Germany. Electronic address:
Article Synopsis
- The study investigates thalamic nuclei changes in females with anorexia nervosa (AN) compared to healthy controls, revealing reduced volumes in most thalamic nuclei.
- Significant associations were found between thalamic alterations, body mass index (BMI), and leptin levels, indicating leptin's role in these changes.
- The findings highlight the thalamus as a crucial area for understanding AN and suggest exploring leptin treatment as a potential intervention.
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