AI Article Synopsis
- Cancer research is increasingly using evolutionary theory to understand how tumors develop and evolve at the genetic level.
- Analyzing chromosomal instability in both cancer cells and different species can provide insights that benefit both research areas.
- This approach allows scientists to uncover the mechanisms behind tumor evolution, leading to better strategies for treatment and understanding of cancer biology.
Article Abstract
Cancer research has recently benefitted from the integration of evolutionary theory to study somatic genome evolution during tumor development. Here, we explore how investigating mechanistic principles of chromosomal instability during both species and somatic evolution can reciprocally inform each field.
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| http://dx.doi.org/10.1016/j.tig.2021.05.003 | DOI Listing |
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