The effect of seasonal variation and lunar cycles on reproductive parameters in dogs is unknown. Lunar cycles have important effects on several biological events. Controversy exists about the influence of lunar cycles on offspring sex ratio. This study examined the sex offspring distribution of 973 puppies (48% females and 52% males) from 150 bitches in Italy between 2015 and 2020. A two-way ANOVA followed by post-hoc -test (Bonferroni correction) was used to analyze the influence of season and lunar phase on offspring sex ratio at conception. Sex offspring distribution was not affected by season, whereas lunar phase had a significant effect (< .05). During the new moon, the proportion of male puppies born was significantly lower than during the full moon phase ( < .05). We conclude that season had no effect on sex offspring distribution. The new moon phase at conception appeared to be related to a lower male sex ratio at birth. Further studies assessing additional factors will help provide a better understanding of the lunar cycle differences observed in the sex ratio distribution of dogs.
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http://dx.doi.org/10.1080/07420528.2021.1933001 | DOI Listing |
Adv Sci (Weinh)
January 2025
State Key Laboratory of Reproductive Medicine and Offspring Health, Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Perfluorohexane sulfonic acid (PFHxS) is extensively used in waterproof coatings and fire-fighting foams, and several studies have found it to be a potential health hazard, but there is still unknown about its effects on spermatogenesis. Our results showed that PFHxS-treated mice have significant reproductive toxicity, including a decrease in sperm count and motility, and the levels of sex hormones (P < 0.05).
View Article and Find Full Text PDFJ Agric Food Chem
January 2025
Henan Key Laboratory of Environmental and Animal Product Safety, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, Henan 471000, China.
Fluoride, a common agricultural additive used to enhance plant resilience and pest control, poses toxicity risks when exposure surpasses safe thresholds, affecting ecosystems and human health. While its reproductive toxicity is recognized, the sex-specific and cross-generational effects remain underexplored. To address this gap, we employed an integrative approach combining transcriptomics (next-generation sequencing (NGS)), bioinformatic network analysis, gut microbiota sequencing, and functional assays.
View Article and Find Full Text PDFBehav Brain Res
January 2025
Department of Psychology, University of Otago, New Zealand. Electronic address:
A majority of people with schizophrenia will experience motor symptoms such as impairments to coordination, balance and motor sequencing. These neurological soft signs are associated with negative social and functional outcomes, and poor disease prognosis. They occur prior to medication exposure, suggesting they are an intrinsic feature of schizophrenia.
View Article and Find Full Text PDFAging Dis
January 2025
School of Public Health, University of Haifa, Haifa 3498838, Israel.
The role of endogenous cannabinoids (endocannabinoids; eCBs) in cognitive-related processes has been demonstrated in preclinical studies. However, observational studies are lacking. We examined the associations of multiple circulating eCBs and eCB-like molecules with cognitive function in a sample of dementia-free older adults.
View Article and Find Full Text PDFJ Psychiatr Res
January 2025
Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, 52246, USA; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA, 52246, USA; Yale Child Study Center, Yale School of Medicine, New Haven, CT, 06510, USA. Electronic address:
Prenatal stress is a risk factor for neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD). However, how early stress modification of brain development contributes to this pathophysiology is poorly understood. Ventral forebrain regions such as dorsal striatum are of particular interest: dorsal striatum modulates movement and cognition, is altered in NDDs, and has a primarily GABAergic population.
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