An integrated optimization model for an organic-waste-derived butyric acid-to-butanol supply-chain network (BABSCN) is proposed to minimize the total network cost by simultaneously optimizing both strategic biodiesel production and waste management planning decisions. This model is useful for ensuring effective organic-waste provision for large-scale biodiesel production and waste management. The proposed mixed-integer linear-programming model optimizes the activities ranging from organic-waste preprocessing to butyric acid (BA), transportation of BA to biorefinery, butanol (BuOH) production and mixing with diesel to the distribution of biodiesel. This model is useful for forecasting organic-waste management biodiesel supply chains in South Korea in 2030. The case study results show that a total network cost of $US 3.16/gallon of B3 contains 3% BuOH from organic waste products combined with diesel. The biorefinery-related cost accounts for 98.3% of the total network cost, followed by the organic waste procurement cost (1.1%) and biodiesel distribution cost (0.6%). A scenario-based analysis shows that a 7%-BuOH increase in biodiesel increases the total network cost by 18.8%.
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http://dx.doi.org/10.1016/j.jenvman.2021.112848 | DOI Listing |
PLoS One
March 2025
Department of Electrical Engineering, Faculty of Engineering, Suez Canal University, Ismailia, Egypt.
In distribution grids, excessive energy losses not only increase operational costs but also contribute to a larger environmental footprint due to inefficient resource utilization. Ensuring optimal placement of photovoltaic (PV) energy systems is crucial for achieving maximum efficiency and reliability in power distribution networks. This research introduces the Pelican Optimizer (PO) algorithm to optimally integrate solar PV systems to radial electrical distribution grids.
View Article and Find Full Text PDFMed Oncol
March 2025
Centre for Biotechnology, Siksha O Anusandhan (Deemed to Be University), Bhubaneswar, Odisha, 751003, India.
Prostate cancer has garnered much importance in recent years due to its rising incidence and mortality among men worldwide. The ineffectiveness of existing therapies and adverse events associated with conventional treatment have led patients to turn towards traditional medicine for the management of prostate cancer. Cinnamomum zeylanicum bark essential oil (CZEO) possesses promising anticancer properties, yet the exact mechanism of action of CZEO for the management of prostate cancer remains unclear.
View Article and Find Full Text PDFEur J Epidemiol
March 2025
Department of Orthopedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark.
Background And Aim: Major lower extremity amputations (MLEA) are common procedures. Potential changes in surgical strategy and patient characteristics over time have not been described previously. The aim of this study was to investigate the incidence rates and surgical strategies of first-time MLEAs over time from 2010 to 2021.
View Article and Find Full Text PDFEpilepsia
March 2025
University of California San Francisco Weill Institute for Neurosciences, Benioff Children's Hospital, San Francisco, California, USA.
Objective: We analyzed the long-term safety and effectiveness of fenfluramine (FFA) in patients with Dravet syndrome (DS) in an open-label extension (OLE) study after participating in randomized controlled trials (RCTs) or commencing FFA de novo as adults.
Methods: Patients with DS who participated in one of three RCTs or were 19 to 35 years of age and started FFA de novo were included. Key endpoints were: incidence of treatment-emergent adverse events (TEAEs) in the safety population, and median percentage change in monthly convulsive seizure frequency (MCSF) from the RCT baseline to end of study (EOS) in the modified intent-to-treat (mITT) population.
Womens Health (Lond)
March 2025
Center for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Background: Retention of weight postpartum increases risk for long-term morbidity, including cardiometabolic disease. Although retained weight postpartum is a complex problem, interventions generally address individual diet and activity behaviors.
Objectives: We investigated the impact of social-network factors on postpartum health behaviors and weight.
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