[Mathematical and computational methods to model chemotherapy- induced resistance].

Magy Onkol

Egyetemi Kutató és Innovációs Központ, Óbudai Egyetem, Élettani Szabályozások Kutatóközpont, Budapest, Hungary.

Published: June 2021

AI Article Synopsis

  • Chemotherapy is a key treatment for cancer, but it often fails, leading to tumor progression even during treatment.
  • Researchers at the Cybermedical Competence Center at Óbuda University are studying mathematical models to understand tumor growth and resistance to therapy.
  • The study emphasizes developing a new concept for optimizing traditional chemotherapy to improve treatment outcomes.

Article Abstract

Chemotherapy plays an important role in the treatment of cancer. While clinical chemotherapy protocols can lead to remission in some patients, in many cases tumor progression occurs despite continued treatment. In the present study we summarize mathematical approaches to model tumor growth and response to treatment, focusing on anticancer therapy resistance. We present results obtained at the recently founded Cybermedical Competence Center at Óbuda University, focusing on the development of a new therapy optimization concept that aims to optimize traditional chemotherapy.

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