Health risk assessment of endocrine disruptor bisphenol A leaching from plastic bottles of milk and soft drinks.

Bisphenol A (BPA) is of major concern to public health due to its toxic potential and xenoestrogenic endocrine-disrupting effect. One of the major sources of BPA comes from the plastic bottles used to pack milk and soft drinks. The purpose of the present study was to assess and compare the risk associated with BPA transfer from plastic bottles to milk and soft drinks being stored in summer and winter conditions. A sensitive and reliable method of solid phase extraction cartridge packed with multi-walled carbon nanotubes (MWCNTs) was employed. In milk samples (supplied in plastic bottles) of winter season, BPA levels were 0.17-0.32 mg/ kg. In milk samples of summer season, BPA levels were 0.77-1.59 mg/ kg. In soft drink samples of winter, BPA levels were between 0.14 and 0.3 mg/kg. While in 4-month-aged summer soft drink samples, BPA levels were 0.7-1.02 mg/kg of food. The daily exposure dose (DED) of BPA in milk samples of winter season was 1.42-2.67 μg/kg which was below the standard tolerable daily intake (TDI) of 50 μg of BPA/kg of body weight as per USEPA. The DED of BPA in milk samples of summer season was 5.58-10 μg/kg of body weight which was also less than TDI. For soft drink samples, BPA from winter samples was ranged from 1.17 to 1.67 μg/kg of body weight while for summer 4-month-aged samples was 2.5-7.08 μg/kg of body weight. Both types of samples were still less than TDI of BPA.