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Shooter's Abscess: Foot Infections in People Who Inject Drugs.
J Am Podiatr Med Assoc
January 2025
*University of Texas Southwestern Medical Center, Department of Plastic Surgery, Dallas, TX.
Musculoskeletal infections are common among people who inject drugs. Little is known about the prevalence and characteristics of skin and soft-tissue infections in this patient population, especially in the lower extremity. The aim of this study is to describe the clinical characteristics, bacterial pathogens, and clinical outcomes in adults with foot infections due to intravenous drug use.
View Article and Find Full Text PDFThe Influence of Substance Use on Sleep Duration Among South Korean Adolescents by Sex: A Secondary Analysis.
J Spec Pediatr Nurs
January 2025
Samsung Medical Center, Seoul, Republic of Korea.
Purpose: Although insufficient sleep influences cognitive function and physical and mental health in adolescents, many still get less sleep than the recommended duration. Adolescent substance use, including alcohol and tobacco, influences sleep disturbance. However, sex differences in the relationship between substance use and sleep health have not been extensively studied.
View Article and Find Full Text PDFQuantifying years of life lost in Australia: a multiple cause of death analysis.
Int J Epidemiol
December 2024
National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australia.
Background: Deaths in Australia and other high-income countries increasingly involve multiple conditions. However, key burden of disease measures typically only use the underlying cause of death (UC). We quantified sex and cause-specific years of life lost (YLL) based on UC compared with a method integrating multiple causes of death.
View Article and Find Full Text PDFFour targets: an enhanced framework for guiding causal inference from observational data.
Int J Epidemiol
December 2024
Program in Addiction Medicine, Yale School of Medicine, New Haven, CT, United States.
Observational studies play an increasingly important role in estimating causal effects of a treatment or an exposure, especially with the growing availability of routinely collected real-world data. To facilitate drawing causal inference from observational data, we introduce a conceptual framework centered around "four targets"-target estimand, target population, target trial, and target validity. We illustrate the utility of our proposed "four targets" framework with the example of buprenorphine dosing for treating opioid use disorder, explaining the rationale and process for employing the framework to guide causal thinking from observational data.
View Article and Find Full Text PDFToxicodynamic insights of 2C and NBOMe drugs - Is there abuse potential?
Toxicol Rep
June 2025
Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Drug use represents a prevalent and multifaceted societal problem, with profound implications for public health, social welfare, and economic stability. To circumvent strict international drug control regulations, there is a growing trend in the development and market introduction of novel psychoactive substances (NPS), encompassing a wide range of compounds with psychoactive properties. This includes, among other classes of drugs, the phenethylamines.
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