Habitual Hyperthermia: An Interpretive Paradigm of the 20th Century? Not Really.

Int J Gen Med

Department of Internal Medicine and Infectious Diseases, Clinique de l'Infirmerie Protestante de Lyon, Caluire-et-Cuire, France.

Published: May 2021

AI Article Synopsis

  • Prolonged unexplained fevers in young adults are rare, particularly with easy access to diagnostic tests, but low-grade fevers typically receive less research attention.
  • A case of a 37-year-old nurse experiencing a three-month intermittent low-grade fever with no clear diagnostic findings exemplifies "habitual hyperthermia" (HH), a condition first identified by virologist Prof. H.A. Reimann.
  • The article emphasizes the need for careful selection of diagnostic tests in family practice for young adults with prolonged fevers and suggests revising surveillance strategies when HH is suspected.

Article Abstract

Prolonged and unexplained fevers in young adults are uncommon, especially when access to diagnostic tests is simplified. Therefore, the definition of unexplained fever depends on the volume of tests performed. However, low-grade fever has not been a priority in research. Management of low-grade fever [eg, an oral temperature of ≥37.8°C (100°F) and <38.3°C (101°F) at any time of the day] is not codified. The presented case of a 37-year-old nurse with an intermittent fever for three months, with no clear diagnostic evidence and no elevated markers of inflammation, illustrates "habitual hyperthermia" (HH)-retained after ordering tests sequentially in town and at the hospital. HH was made known by Prof. H.A. Reimann (1897-1986) an American virologist, although the diagnostic criteria are fallible. The article reviews the criteria and then discusses how to select diagnostic tests in family practice for prolonged fever in young adults without clinical signs of orientation. Given the polymorphism of febrile illnesses, the principle of parsimony must be transgressed, and in the event of an early suspicion of HH, surveillance is a rule to be further amended.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164870PMC
http://dx.doi.org/10.2147/IJGM.S306423DOI Listing

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