Objectives: To investigate prevalence and association between iron deficiency anemia (IDA) and ).
Methods: This cross-sectional study included 79 participants with unexplained IDA. The study was carried out between November 2018 to April 2020 in the College of Medicine, Umm Al-Qura University in collaboration with Al-Noor Specialist Hospital, Makkah, Saudi Arabia. Complete blood count (CBC), serum iron, and ferritin levels were measured. Anti- antibody was detected using anti- immunoglobulin G enzyme-linked immunosorbent assay (ELISA).
Results: The prevalence of infection among IDA patients was 62%. There was a significant difference between female and male subjects with a positive status (=0.001). There was also a significant difference between females and males with a positive infection according to red blood cell count, hematocrit, mean corpuscular volume, and mean cor-puscular hemoglobin (=0.001).
Conclusion: The current study shows an association between infection and unexplained IDA with significant difference between postmenopausal Saudi females and males. This will lead to more effective treatment in IDA and the eradication of , as well as the prevention of recurrence, which are necessary and may provide a significant reduction in the overall disease burden.
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http://dx.doi.org/10.15537/smj.2021.42.6.20210103 | DOI Listing |
Intern Med J
December 2024
Internal Medicine Services, The Prince Charles Hospital, Brisbane, Queensland, Australia.
Background: Iron deficiency anaemia (IDA) related to occult gastrointestinal tract (GIT) blood loss is associated with high rates of GIT malignancies. Major society guidelines recommend bidirectional endoscopic evaluation for all men and post-menopausal women with newly diagnosed, unexplained IDA. However, in patients prescribed direct oral anticoagulants (DOACs), the endoscopic yield, specifically the rate of high-risk findings, including colorectal cancers (CRCs) and advanced adenomas (AAs), is unknown.
View Article and Find Full Text PDFJ Pediatr Hematol Oncol
July 2024
Departments of Pediatrics.
Front Epidemiol
February 2023
Department of Neurology, Christian-Doppler University Hospital, Paracelsus Medical University, Centre for Cognitive Neuroscience, Member of EpiCARE, Salzburg, Austria.
Patients with epilepsy carry a risk of premature death which is on average two to three times higher than in the general population. The risk of death is not homogenously distributed over all ages, etiologies, and epilepsy syndromes. People with drug resistant seizures carry the highest risk of death compared to those who are seizure free, whose risk is similar as in the general population.
View Article and Find Full Text PDFJ Am Med Dir Assoc
June 2024
Department of Primary and Long-Term Care, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:
Objectives: Guidelines recommend upper and lower gastrointestinal endoscopic evaluation for patients without a clear physiological explanation for iron deficiency anemia (IDA). However, the consequences of watchful waiting in older patients with unexplained IDA in general practice are unknown. The aim of this study was to investigate characteristics and survival of patients with an unexplained IDA in general practice who refrain from medical specialist evaluation.
View Article and Find Full Text PDFJ Family Med Prim Care
August 2023
Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, Delhi, India.
Background: Inflammation has several effects in the geriatrics with reference to iron deficiency anemia (IDA), anemia of chronic disease (ACD), and unexplained anemia (UA). Whether hyperinflammation is part of their pathogenesis or just incidental is unknown. Data are limited regarding inflammatory patterns in IDA, ACD, and UA in anemic geriatrics and inflammation as a component of UA.
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