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With an estimated incidence of 0.02% to 0.2%, multiligamentous knee injuries are rare, often devastating injuries that can occur with concomitant vascular or neurologic involvement.
View Article and Find Full Text PDFUlnar collateral ligament injury of the elbow is a problem most associated with baseball pitchers but can be a challenging pathology for any overhead throwing athlete. The prevalence of these injuries has been steadily increasing over the past several decades, as has the need for surgical management. Surgical reconstruction has long been considered the gold standard for complete ulnar collateral ligament injuries in throwers, but repair has surfaced as a viable option for younger patients or those with isolated proximal or distal injuries with good tissue quality.
View Article and Find Full Text PDFThe evolving concepts of KS-WNK1 effect on NCC activity.
Am J Physiol Renal Physiol
December 2024
Molecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Tlalpan, Mexico City, 14080 Mexico.
The field of the with no lysine kinases (WNKs) regulation of the thiazide-sensitive NaCl cotransporter (NCC) began at the start of the century with the discovery that mutations in two members of the family, WNK1 and WNK4, resulted in a condition known as Familiar Hyperkalemic Hypertension (FHHt). Since FHHt is the mirror image of Gitelman's syndrome that is caused by inactivating mutations of the SLC12A3 gene encoding NCC, it was expected that WNKs modulated NCC activity and that the increased function of the cotransporter is the pathophysiological mechanism of FFHt. This turned out to be the case.
View Article and Find Full Text PDFSplenic artery embolization for trauma: a narrative review.
J Trauma Inj
December 2024
Department of Interventional Radiology, St. Luke's University Hospital, Bethlehem, PA, USA.
The management of traumatic splenic injuries has evolved significantly over the past several decades, with the majority of these injuries now being treated nonoperatively. Patients who exhibit hemodynamic instability upon initial evaluation typically require surgical intervention, while the remainder are managed conservatively. Conservative treatment for traumatic splenic injuries encompasses both medical management and splenic artery angiography, followed by embolization in cases where patients exhibit clinical signs of ongoing splenic hemorrhage.
View Article and Find Full Text PDFLong-term Outcomes 18 Years after the Arthroscopic Fixation of a Scapular Articular Fracture: A Case Report.
Rev Bras Ortop (Sao Paulo)
November 2024
Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brasil.
Reduction and fixation of glenoid cavity fractures using arthroscopy cause little surgical trauma, allowing the complementary diagnosis and treatment of potentially associated injuries (either capsular, ligamentous or tendon lesions) with promising outcomes. The authors report a case of Ideberg type III glenoid fracture with a distal clavicle fracture which underwent percutaneous reduction and bone fixation (with Kirschner wires) using an arthroscopic technique. We describe the procedure and the outcomes after 18 years of follow-up.
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