A case of infective colitis due to Yersinia enterocolitica complicated by microliver abscesses mimicking multiple liver occult metastases: a case report.

BMC Infect Dis

U.O.C di Medicina Interna con Stroke Care, Dipartimento di Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza "G. D'Alessandro", University of Palermo, Via del Vespro 129, 90127, Palermo, Italy.

Published: June 2021

Background: We report an unusual case of infective colitis by Yersinia enterocolitica complicated by microliver abscesses mimicking multiple liver metastases in a 79 yr old female without any risk factors for bacteriaemia by this pathogen.

Case Presentation: The patient was admitted to the Internal Medicine with Stroke Care ward of University Policlinico "P. Giaccone" in Palermo because of the appearance of diarrhoea. After the antimicrobial treatment for infective colitis, the clinicians observed a persistently increased white blood cells (WBC) count and multiple hepatic lesions; after having excluded any neoplastic disease and inflammatory bowel disease (IBD), blood cultures positive for Y. enterocolitica allowed to establish the final diagnosis was infective micro liver abscesses consequent to infective colitis due to Y. enterocolitica, which were successfully treated with cefixime and doxycycline.

Conclusions: This case report should make clinicians reflect on how complex the differential diagnosis between microliver abscesses and metastasis could be and the possibility of bacteriaemia by Y. enterocolitica even without iron overload conditions.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173975PMC
http://dx.doi.org/10.1186/s12879-021-06177-6DOI Listing

Publication Analysis

Top Keywords

infective colitis
16
microliver abscesses
12
case infective
8
colitis yersinia
8
yersinia enterocolitica
8
enterocolitica complicated
8
complicated microliver
8
abscesses mimicking
8
mimicking multiple
8
multiple liver
8

Similar Publications

Background: Recent biomedical research has shown the unusual, multisystem effects of coronavirus disease 2019 in humans. One specific sequela of a primary severe acute respiratory syndrome coronavirus 2 infection is the reactivation of latent viruses in various tissues, such as Epstein-Barr virus. Epstein-Barr virus has been identified in many inflammatory gastrointestinal lesions, such as microscopic gastritides and colitides.

View Article and Find Full Text PDF

Introduction: Children with inflammatory bowel disease (IBD) need surgery whenever medical therapy fails. The postoperative course is frequently accompanied by symptoms suggestive of infection, such as fever. The aim of our study was to analyze the postoperative course after bowel resection in pediatric IBD patients in relation to postoperative infections.

View Article and Find Full Text PDF

Background: Medically refractory Crohn's disease (CD) is associated with a high risk of complications. Mycophenolate mofetil (MMF), a small molecule immunosuppressant, has limited data in patients with CD, and objective endoscopic response to MMF has not been reported.

Aims: We evaluated the safety and clinical, endoscopic, and biochemical effectiveness of off-label MMF for refractory CD as monotherapy or in combination with a biologic in patients with CD.

View Article and Find Full Text PDF
Article Synopsis
  • - The study explores the potential of chlorquinaldol (CQ), an antimicrobial agent, as a specific inhibitor of the NLRP3 inflammasome, which is linked to various inflammatory diseases, highlighting its promise for drug repurposing.
  • - CQ effectively suppresses NLRP3 inflammasome activation in both mouse and human macrophages primarily by blocking the interaction between NLRP3 and ASC, while having minimal impact on other inflammasomes like NLRC4 and AIM2.
  • - In vivo tests showed that CQ significantly improves conditions in mouse models of LPS-induced peritonitis, DSS-induced colitis, and MSU-induced gouty arthritis, suggesting its therapeutic potential for treating NLRP3-related
View Article and Find Full Text PDF

Flavonifractor plautii bacteremia following bacterial translocation from the gut: A case report and literature review.

J Infect Chemother

December 2024

Department of Infectious Diseases, Nagoya University Hospital, Aichi, Japan; Department of Infectious Diseases, Nagoya University Graduate School of Medicine, Aichi, Japan.

A 75-year-old male, hospitalized with back pain, remained hospitalized for tests for unexplained colitis, which was diagnosed as inflammatory bowel disease unclassified and treated with antibiotics and prednisolone, resulting in Clostridioides difficile colitis. Therefore, antibiotics were discontinued, and oral metronidazole treatment was initiated; however, as the patient's fever persisted, blood cultures were performed. An anaerobic bottle of blood culture turned positive the following day.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!