AI Article Synopsis
- Hantavirus pulmonary syndrome (HPS) is a serious disease linked to New World hantaviruses, primarily caused by the Sin Nombre virus (SNV) found in deer mice.
- Since its discovery in 1993, over 800 cases have been reported in the US, with 43 cases specifically in Montana.
- A study conducted in the Bitterroot Valley revealed a high prevalence (up to 20%) of SNV RNA in deer mice, indicating that the virus continues to circulate in the region.
Article Abstract
Hantavirus pulmonary syndrome (HPS) is an often-fatal disease caused by New World hantaviruses, such as (SNV). In the US, >800 cases of HPS have been confirmed since it was first discovered in 1993, of which 43 were reported from the state of Montana. The primary cause of HPS in the US is SNV, which is primarily found in the reservoir host (deer mouse). The reservoir host covers most of the US, including Montana, where multiple studies found SNV in local deer mouse populations. This study aimed to check the prevalence of SNV in the deer mice at popular recreation sites throughout the Bitterroot Valley in Western Montana as compared to previous studies in western Montana. We found high prevalence (up to 20%) of deer mice positive for SNV RNA in the lungs. We were unable to obtain a SNV tissue culture isolate from the lungs but could passage SNV from lung tissue into naïve deer mice. Our findings demonstrate continuing circulation of SNV in western Montana.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226622 | PMC |
| http://dx.doi.org/10.3390/v13061006 | DOI Listing |
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