Over the last decade, there has been considerable and increasing interest in the development of Active and Assisted Living (AAL) systems to support independent living. The demographic change towards an aging population has introduced new challenges to today's society from both an economic and societal standpoint. AAL can provide an arrary of solutions for improving the quality of life of individuals, for allowing people to live healthier and independently for longer, for helping people with disabilities, and for supporting caregivers and medical staff. A vast amount of literature exists on this topic, so this paper aims to provide a survey of the research and skills related to AAL systems. A comprehensive analysis is presented that addresses the main trends towards the development of AAL systems both from technological and methodological points of view and highlights the main issues that are worthy of further investigation.
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http://dx.doi.org/10.3390/s21103549 | DOI Listing |
Sensors (Basel)
January 2025
University of Zagreb, Faculty of Transport and Traffic Sciences, Vukelićeva 4, 10000 Zagreb, Croatia.
The possibilities of the Ambient Assisted Living (AAL)/Enhanced Living Environments (ELE) concept in the environment of a smart home were investigated to improve accessibility and improve the quality of life of a person with disabilities. This paper focuses on the concept of predictive information for a person with disabilities in a smart home environment concept where artificial intelligence (AI) and machine learning (ML) systems use data on the user's preferences, habits, and possible incident situations. A conceptual mathematical model is proposed, the purpose of which is to provide predictive user information from defined data sets.
View Article and Find Full Text PDFBMC Geriatr
December 2024
Research Department, Reha Rheinfelden, Rheinfelden, Switzerland.
Background: Exergames are interactive technology-based exercise programs. By combining physical and cognitive training components, they aim to preserve independence in older adults and reduce their risk of falling. This study explored whether primary end users (PEU, healthy older adults and patients with neurological and geriatric diagnoses) and secondary end users (SEU, health professionals) evaluated the ExerG functional model to be usable, providing a positive experience and therefore acceptable.
View Article and Find Full Text PDFChem Biol Drug Des
December 2024
Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
The immune system is essential for the defense against infections and is critically implicated in various disorders, including immunodeficiency, autoimmunity, inflammation and cancer. The current study includes a new design of palmitoylated derivatives of thioglycolic acids (PTGAs) capable of triggering innate immune responses. The new series were accessible through a three-step synthetic route, including N-palmitoylation, Claisen-Schmidt condensation and thia-Michael addition.
View Article and Find Full Text PDFAnn Anat
December 2024
University of Bari Aldo Moro, Veterinary Clinics and Animal Production Unit, Department of Precision and Regenerative Medicine and Ionian Area, Bari, Puglia, Italy.
Background: The giant anteater (Myrmecophaga tridactyla) is a toothless mammal that feeds mainly on termites and ants. Therefore, like other toothless mammals, this species has morphological and physiological adaptations of the salivary glands related to eating habits. Saliva is essential for the health of the oral cavity, chewing and lubrication of the mouth and it is constituted by an aqueous fluid containing electrolytes, enzymes, and glycoproteins which play an important role in modulating the oral microbiota.
View Article and Find Full Text PDFNat Commun
November 2024
McEwen Stem Cell Institute, University Health Network, Toronto, ON, Canada.
The sinoatrial node regulates the heart rate throughout life. Failure of this primary pacemaker results in life-threatening, slow heart rhythm. Despite its critical function, the cellular and molecular composition of the human sinoatrial node is not resolved.
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