A novel method of analog-to-information conversion-the random interval integration-is proposed and studied in this paper. This method is intended primarily for compressed sensing of aperiodic or quasiperiodic signals acquired by commonly used sensors such as ECG, environmental, and other sensors, the output of which can be modeled by multi-harmonic signals. The main idea of the method is based on input signal integration by a randomly resettable integrator before the AD conversion. The integrator's reset is controlled by a random sequence generator. The signal reconstruction employs a commonly used algorithm based on the minimalization of a distance norm between the original measurement vector and vector calculated from the reconstructed signal. The signal reconstruction is performed by solving an overdetermined problem, which is considered a state-of-the-art approach. The notable advantage of random interval integration is simple hardware implementation with commonly used components. The performance of the proposed method was evaluated using ECG signals from the MIT-BIH database, multi-sine, and own database of environmental test signals. The proposed method performance is compared to commonly used analog-to-information conversion methods: random sampling, random demodulation, and random modulation pre-integration. A comparison of the mentioned methods is performed by simulation in LabVIEW software. The achieved results suggest that the random interval integration outperforms other single-channel architectures. In certain situations, it can reach the performance of a much-more complex, but commonly used random modulation pre-integrator.
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http://dx.doi.org/10.3390/s21103543 | DOI Listing |
Blood Adv
January 2025
Ente Ospedaliero Cantonale, Switzerland.
The Swiss Group for Clinical Cancer Research (SAKK) and the Nordic Lymphoma Group (NLG) conducted the SAKK 35/10 randomized phase-2 trial (NCT0137605) to compare rituximab (R) alone versus R plus lenalidomide (L) as initial treatment for follicular lymphoma (FL). Patients with grade 1-3a FL, requiring systemic therapy, were randomized to either R (n=77; 375 mg/m2 IV x 1, weeks 1-4) or RL (n=77; R on the same schedule and L at 15 mg daily continuously). Responders (evaluated at 10 weeks) repeated R during weeks 12-15 with or without L (for a total of 18 weeks).
View Article and Find Full Text PDFJ Glob Health
January 2025
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Recreational screen time (RST) has been found to be associated with cognitive decline and neurodegenerative diseases. However, the association between RST and age-related macular degeneration (AMD), an ocular neurodegenerative disease, is still unclear. We aimed to elucidate the association between RST and AMD.
View Article and Find Full Text PDFRejuvenation Res
January 2025
Nutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
The study aimed to explore the association between different sleep traits and all-cause mortality as well as to validate causality in the association through mendelian randomization (MR). We analyzed 451,420 European ancestry participants from the UK Biobank. Multivariable-adjusted Cox proportional hazards model was conducted to evaluate the association between sleep traits and all-cause mortality.
View Article and Find Full Text PDFEnviron Health Perspect
January 2025
Scripps Institution of Oceanography, San Diego, California, USA.
Background: The increasing frequency and severity of extreme heat events due to climate change present unique risks to children and adolescents. There is a lack of evidence regarding how heat's impacts on pediatric patients vary spatially and how structural and sociodemographic factors drive this heterogeneity.
Objectives: We examined the association between extreme heat events and pediatric acute care utilization in California for 19 distinct health conditions.
Pulmonology
December 2025
Respiratory Rehabilitation Unit, Istituti Clinici Scientifici Maugeri IRCCS, Lumezzane, Italy.
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