This study describes a simple, practical, inexpensive, improved, and efficient novel method for obtaining polyurea-polyurethane-multiwall carbon nanotubes (MWCNTs) nanocomposites with enhanced mechanical properties, and their experimental testing in a dynamic regime. SEM and micro-CT investigations validated the homogeneity of the nanocomposite films and uniform dispersion of the nanofiller inside the polymeric matrix. The experimental measurements (TGA, DSC, DMA, and tensile tests) revealed improved thermal and mechanical properties of these new materials. To demonstrate that these nanocomposites are suitable for ballistic protection, impact tests were performed on aluminum plates coated with the polyurea-polyurethane MWCNTs nanocomposites, using a Hopkinson bar set-up. The experimental testing in the dynamic regime of the polyurea- polyurethane-coated aluminum plates confirmed that the nanocomposite layers allow the metal plate to maintain its integrity at a maximum force value that is almost 200% higher than for the uncoated metallic specimens.
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http://dx.doi.org/10.3390/polym13101618 | DOI Listing |
Gynecol Oncol
January 2025
GOG Foundation, Florida Cancer Specialists and Research Institute, West Palm Beach, FL 33401, United States of America. Electronic address:
Objective: Therapeutic interventions for epithelial ovarian cancer (EOC) have increased greatly over the last decade but improvements outside of biomarker selected therapies have been limited. There remains a pressing need for more effective treatment options that can prolong survival and enhance the quality of life of patients with EOC. In contrast to the significant benefits of immunotherapy with immune checkpoint inhibitors (CPI) seen in many solid tumors, initial experience in EOC suggests limited efficacy of CPIs monotherapy.
View Article and Find Full Text PDFPurpose: To theoretically and experimentally study implant lead tip heating caused by radiofrequency (RF) power deposition in different wire configurations that contain loop(s).
Methods: Maximum temperature rise caused by RF heating was measured at 1.5T on 20 insulated, capped wires with various loop and straight segment configurations.
Rare diseases are collectively common, affecting approximately one in twenty individuals worldwide. In recent years, rapid progress has been made in rare disease diagnostics due to advances in DNA sequencing, development of new computational and experimental approaches to prioritize genes and genetic variants, and increased global exchange of clinical and genetic data. However, more than half of individuals suspected to have a rare disease lack a genetic diagnosis.
View Article and Find Full Text PDFCancer immunotherapy using engineered cytotoxic effector cells has demonstrated significant potential. The limited spatial complexity of existing models, however, poses a challenge to mechanistic studies attempting to approve existing approaches of effector cell-mediated cytotoxicity within a three-dimensional, solid tumor-like environment. To gain additional experimental control, we developed an approach for constructing three-dimensional (3D) culture models using smart polymers that form temperature responsive hydrogels.
View Article and Find Full Text PDFUnlabelled: The reflexive translation of symbols in one chemical language to another defined genetics. Yet, the co-linearity of codons and amino acids is so commonplace an idea that few even ask how it arose. Readout is done by two distinct sets of proteins, called aminoacyl-tRNA synthetases (AARS).
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