A dual liquid-crystal variable retarder Mueller polarimetry system incorporating a gold-based surface plasmon resonance prism coupler was proposed for extracting the optical properties of serum albumin protein media in the reflectance configuration. The feasibility of the proposed system was demonstrated by measuring the circular dichroism and circular birefringence properties of glucose tissue phantom solutions with different albumin concentrations. The results showed that the circular dichroism increased with albumin concentration, while the optical rotation angle increased with glucose concentration. Both properties reduced over time as a result of the protein glycation effect, which led to a gradual reduction in the glucose content of the sample.
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http://dx.doi.org/10.3390/s21103442 | DOI Listing |
Optical polarization is three-dimensional (3-D). Its complete information is described by the nine-component generalized Stokes vector (GSV). However, existing Stokes polarimetry and its design theory are primarily based on the paraxial four-component Stokes vector and 4 × 4 Mueller matrices.
View Article and Find Full Text PDFJ Med Imaging (Bellingham)
January 2025
University of Arizona, College of Biomedical Engineering, Tucson, Arizona, United States.
Purpose: Diffusion magnetic resonance imaging (dMRI) quantitatively estimates brain microstructure, diffusion tractography being one clinically utilized framework. To advance such dMRI approaches, direct quantitative comparisons between microscale anisotropy and orientation are imperative. Complete backscattering Mueller matrix polarized light imaging (PLI) enables the imaging of thin and thick tissue specimens to acquire numerous optical metrics not possible through conventional transmission PLI methods.
View Article and Find Full Text PDFJ Med Imaging (Bellingham)
November 2024
University of Arkansas, Department of Electrical Engineering and Computer Science, Fayetteville, Arkansas, United States.
Front Optoelectron
December 2024
Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.
Achilles tendon injuries, as a widely existing disease, have attracted a lot of research interest. Mueller matrix polarimetry, as a novel label-free quantitative imaging method, has been widely used in various applications of lesion identification and pathological diagnosis. However, focusing on the recovery process of Achilles tendon injuries, current optical imaging methods have not yet achieved the label-free precise identification and quantitative evaluation.
View Article and Find Full Text PDFComputational Mueller matrix polarimetry holds great promise in biomedical studies and clinical applications, providing comprehensive polarization-related vectorial information within the sample. For backscattering polarization imaging systems aimed at in vivo tissue polarimetry, the measurement results can be affected by the Cartesian coordinates transformation due to the vectorial properties of polarized light and the non-collinear characteristics of the measurement system. It can influence the reliability of polarization information decoding and extraction.
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