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Repurposing Licensed Drugs with Activity Against Epstein-Barr Virus for Treatment of Multiple Sclerosis: A Systematic Approach.
CNS Drugs
January 2025
School of Medicine and Dentistry, Gold Coast Campus, Griffith University, Southport, QLD, 4222, Australia.
Background: Epstein-Barr virus (EBV) is implicated as a necessary factor in the development of multiple sclerosis (MS) and may also be a driver of disease activity. Although it is not clear whether ongoing viral replication is the driver for MS pathology, MS researchers have considered the prospect of using drugs with potential efficacy against EBV in the treatment of MS. We have undertaken scientific and lived experience expert panel reviews to shortlist existing licensed therapies that could be used in later-stage clinical trials in MS.
View Article and Find Full Text PDF[Roles of Trophoblast Differentiation, Cell Fusion, and Microvilli Formation in Placentation and Prospects for a Model for Their Assessment].
Yakugaku Zasshi
January 2025
Department of Endocrine Pharmacology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences.
The placenta, which acts as an interface between fetal and maternal circulations, is an indispensable organ for fetal growth in mammalian pregnancy. It mediates the transportation of nutrients, the exchange of gases such as oxygen and carbon dioxide, and the excretion of waste products between the fetus and mother. The surface of placental villi is covered by two layers of mononuclear undifferentiated cytotrophoblasts (CT) and multinucleated syncytiotrophoblasts (ST).
View Article and Find Full Text PDFThe year 2025 marks the 50th anniversary of the publication of the first paper by Dr. P.J.
View Article and Find Full Text PDF[The Roles of Pharmacists and Pharmacies in Sustainable Medical Care: Current Status and Outlook Three Years After the Issuance of Recommendations by the Science Council of Japan].
Yakugaku Zasshi
December 2024
Faculty of Pharmaceutical Sciences, Teikyo University.
Three years have passed since the Science Council of Japan issued its recommendations entitled "Profession and lifelong learning of pharmacists responsible for sustainable medical care." These recommendations include active involvement in community medicine, securing patient information necessary for pharmaceutical management, harmonizing undergraduate and post-graduate education, reform of the certification system for specialty-credentialed pharmacists, and development of the pharmacist resident system. This paper provides an overview of recent trends and future prospects for pharmacists and pharmacies in Japan.
View Article and Find Full Text PDF[Future Prospects of the Project to Develop Remote Robotic Surgery via a Commercial 5G Network Using the hinotori TM Surgical Robot System].
Gan To Kagaku Ryoho
October 2024
Kobe University, International Clinical Cancer Research Center.
We describe the background, current status, status of competing countries, and future prospects of the project to develop remote robotic surgery via a commercial 5G network using the hinotoriTM Surgical Robot System.
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