AI Article Synopsis
- Biomarkers are measurable indicators of health status, useful for early disease detection, especially in patients undergoing radiation therapy for head and neck cancer.
- Xerostomia, or dry mouth, is a common side effect of radiation, and saliva contains protein biomarkers that need further research in this context.
- The review focuses on identifying salivary protein and imaging biomarkers that can help predict and manage xerostomia in these patients.
Article Abstract
Biomarkers are anatomical characteristics or naturally occurring measurable molecules indicating physiological or pathological state of an individual. These biomarkers have the potential to detect or predict diseases at an early stage, which is particularly beneficial in timely management of common complications of radiation therapy done in head and neck cancer treatment regime. Xerostomia is one of the most common oral complaints of radiation therapy. Saliva has an abundance of protein biomarkers; however, those related to post-radiation therapy xerostomia need to be explored further. Textural and imaging-based biomarkers are helpful in predicting xerostomia in such patients. This narrative review provides an account of salivary protein and imaging-based biomarkers of radiation therapy-induced xerostomia in head and neck cancer patients.
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| http://dx.doi.org/10.47391/JPMA.1115 | DOI Listing |
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