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| http://dx.doi.org/10.1111/tme.12792 | DOI Listing |
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Risk impact of SARS-CoV-2 coronavirus and spike protein on cardiac tissue: a comprehensive review.
Physiol Res
December 2024
Laboratory of Neurobiology and Molecular Psychiatry, Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic.
The global COVID-19 pandemic, caused by SARS-CoV-2, has led to significant morbidity and mortality, with a profound impact on cardiovascular health. This review investigates the mechanisms of SARS-CoV-2's interaction with cardiac tissue, particularly emphasizing the role of the Spike protein and ACE2 receptor in facilitating viral entry and subsequent cardiac complications. We dissect the structural features of the virus, its interactions with host cell receptors, and the resulting pathophysiological changes in the heart.
View Article and Find Full Text PDFBackground: Epidemics and pandemics have been shown to have widespread effects on health systems. Diabetes is a condition of particular risk during national emergencies such as the COVID-19 pandemic. The aim of this study is to determine the influence of COVID-19 in the patient's diabetes quality management.
View Article and Find Full Text PDFDisparities in response to mRNA SARS-CoV-2 vaccines according to sex and age: A systematic review.
New Microbes New Infect
February 2025
Department of Global and Public Health, Epidemiology, Biostatistics and Prevention Institute, WHO Collaborating Centre for Travellers' Health, Centre of Competence for Military Medicine Biology, University of Zürich, Switzerland.
Background: The rapid development and distribution of mRNA COVID-19 vaccines has been essential in containing the SARS-CoV-2 epidemic around the globe. For ongoing and future immunization campaigns globally, there is a need to evaluate the impact of population demographics such as age and sex, on vaccine efficacy and safety.
Methods: This systematic review (PROSPERO ID CRD42023328245) conducted according to PRISMA guidelines evaluates the impact of age and sex on the safety and efficacy of the mRNA COVID-19 vaccinations administrated in 15 studies that were chosen according to strict criteria.
Balancing mitigation strategies for viral outbreaks.
Math Biosci Eng
December 2024
Department of Mathematics & Statistics, Georgia State University, Atlanta, USA.
Control and prevention strategies are indispensable tools for managing the spread of infectious diseases. This paper examined biological models for the post-vaccination stage of a viral outbreak that integrate two important mitigation tools: social distancing, aimed at reducing the disease transmission rate, and vaccination, which boosts the immune system. Five different scenarios of epidemic progression were considered: (ⅰ) the "no control" scenario, reflecting the natural evolution of a disease without any safety measures in place, (ⅱ) the "reconstructed" scenario, representing real-world data and interventions, (ⅲ) the "social distancing control" scenario covering a broad set of behavioral changes, (ⅳ) the "vaccine control" scenario demonstrating the impact of vaccination on epidemic spread, and (ⅴ) the "both controls concurrently" scenario incorporating social distancing and vaccine controls simultaneously.
View Article and Find Full Text PDFImpact of Government Healthcare Policy Changes on Consumption and Human Movements During COVID-19: An Interrupted Time Series Analysis in Korea.
J Korean Med Sci
January 2025
Department of Preventive Medicine, Gachon University College of Medicine, Incheon, Korea.
Background: The coronavirus disease 2019 (COVID-19) pandemic has altered daily behavioral patterns based on government healthcare policies, including consumption and movement patterns. We aimed to examine the extent to which changes in the government's healthcare policy have affected people's lives, primarily focusing on changes in consumption and population movements.
Methods: We collected consumption data using weekly credit card transaction data from the Hana Card Corporation and population mobility data using mobile phone data from SK Telecom in Seoul, South Korea.
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