Emerging Preclinical and Clinical Applications of Theranostics for Nononcological Disorders.

PET Clin

Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany; Department of Nuclear Medicine, Klinikum Westfalen, Am Knappschaftskrankenhaus 1, Dortmund 44309, Germany. Electronic address:

Published: July 2021

Studies in nuclear medicine have shed light on molecular imaging and therapeutic approaches for oncological and nononcological conditions. Using the same radiopharmaceuticals for diagnosis and therapeutics of malignancies, the theranostics approach, has improved clinical management of patients. Theranostic approaches for nononcological conditions are recognized as emerging topics of research. This review focuses on preclinical and clinical studies of nononcological disorders that include theranostic strategies. Theranostic approaches are demonstrated as possible in the clinical management of infections and inflammations. There is an emerging need for randomized trials to specify the factors affecting validity and efficacy of theranostic approaches in nononcological diseases.

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Source
http://dx.doi.org/10.1016/j.cpet.2021.03.009DOI Listing

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