AI Article Synopsis
- Exercise intolerance is a common issue in heart failure with preserved ejection fraction (HFpEF), leading to a lower quality of life and higher rates of hospitalization and mortality.
- * The cardiopulmonary exercise test is crucial for measuring exercise tolerance and understanding the specific causes of limitations in patients with HFpEF, which can guide treatment.
- * Exercise training programs can enhance exercise tolerance in HFpEF patients, but more research is needed to determine the most effective types and durations of these programs.*
Article Abstract
Exercise intolerance represents a typical feature of heart failure with preserved ejection fraction (HFpEF), and is associated with a poor quality of life, frequent hospitalizations, and increased all-cause mortality. The cardiopulmonary exercise test is the best method to quantify exercise intolerance, and allows detection of the main mechanism responsible for the exercise limitation, influencing treatment and prognosis. Exercise training programs improve exercise tolerance in HFpEF. However, studies are needed to identify appropriate type and duration. This article discusses the pathophysiology of exercise limitation in HFpEF, describes methods of determining exercise tolerance class, and evaluates prognostic implications and potential therapeutic strategies.
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| http://dx.doi.org/10.1016/j.hfc.2021.03.004 | DOI Listing |
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