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A case of bacteremia caused by Leptotrichia trevisanii in pediatric patient with febrile neutropenia and review of literature. | LitMetric

A case of bacteremia caused by Leptotrichia trevisanii in pediatric patient with febrile neutropenia and review of literature.

Acta Microbiol Immunol Hung

Department of Medical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Published: May 2021

AI Article Synopsis

  • Leptotrichia species are gram-negative bacilli found in human microbiota and have become notable opportunistic pathogens, particularly in immunocompromised individuals.
  • A case study identified Leptotrichia trevisanii in a five-year-old boy's central venous catheter culture, using advanced identification techniques like mass spectrometry and gene sequencing.
  • Early detection of anaerobic bacteremia and timely antimicrobial treatment are crucial for preventing serious health complications in pediatric patients.

Article Abstract

Leptotrichia species are fastidious anaerobic, fusiform, pencil-shaped Gram-negative bacilli that reside in microbiota of humans. Leptotrichia species have increasingly been recognized as an opportunistic pathogen in humans, mainly in the immunocompromised patient. Anaerobic organisms have rarely been isolated from blood cultures of pediatric patients. In our study, we isolated Leptotrichia trevisanii from central venous catheter culture of a five-year-old male patient. It was identified with both matrix-assisted laser desorption ionization time-of-flight mass spectrometry and confirmed via 16S rRNA gene sequencing. The early recognition of anaerobic bacteremia and administration of appropriate antimicrobial and play an important role preventing mortality and morbidity in children. In our study we report a rarely diagnosed case of L. trevisanii bacteremia in a pediatric patient.

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Source
http://dx.doi.org/10.1556/030.2021.01358DOI Listing

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