54 patients with severe tinnitus were treated by lidocaine iontophoresis. 25 patients suffered from a bilateral tinnitus. A total of 75 ears were treated. The ratio of male to female patients was 3:1. The average age was 45 years. All patients had got over at least one ineffective treatment. Prior to iontophoresis a complete audiologic, neuro-otologic and x-ray examination of the temporal bones was performed. In all patients the frequency and intensity of tinnitus were determined before and immediately after a treatment. In 44 patients there was no difference in their tinnitus after the treatment. In one patient the tinnitus has become lower by the iontophoresis. The value of this method in tinnitus therapy is discussed.
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Noise Health
January 2025
Department of Otolaryngology, Head and Neck Surgery, Changde Hospital, Xiangya School of Medicine, Central South University (The First People's Hospital of Changde City), Changde 415000, Hunan, China.
Objective: In this study, the research team aimed to explore the therapeutic effectiveness of hyperbaric oxygen therapy (HBOT) for noise-induced hearing loss (NIHL), its influence on patient prognosis, and its impact on hearing to provide valuable clinical evidence.
Methods: Ninety-four patients with NIHL admitted to The First People's Hospital of Changde City, Hunan, China, from May 2021 to January 2023 were selected for this retrospective analysis. Among them, 43 were given conventional treatment (control group) and 51 were given HBOT (observation group).
The recent ACHIEVE study (https://www.achievestudy.org/) demonstrated the substantial benefit of hearing aid use in those with mild-moderate hearing loss and at increased risk for cognitive decline.
View Article and Find Full Text PDFBr J Pain
January 2025
Department of Pain Medicine and Neuromodulation, The Walton centre NHS foundation Trust, Liverpool, UK.
Although spinal cord stimulator (SCS) therapy is generally used safely to treat chronic neuropathic pain conditions, this document highlights the less reported complication of unusual neurological problems including headaches. These developed temporally after the initiation of SCS therapy despite initial positive response to pain. The mechanisms might include activation of trigeminal receptors and neuroplasticity after SCS.
View Article and Find Full Text PDFMolecules
December 2024
College of Pharmacy, Nantong University, Nantong 226000, China.
L., a species within the genus, is broadly distributed across Southern Europe and Central Asia. In China, its berries, branches, and leaves are traditionally employed in Uyghur medicine to address conditions such as rheumatoid arthritis, itchy skin, tinnitus, deafness, and urinary discomfort.
View Article and Find Full Text PDFAntioxidants (Basel)
December 2024
Institute of Pharmacology and Toxicology, Paracelsus Medical University, 5020 Salzburg, Austria.
Cisplatin is an established component of treatment protocols for various solid malignancies but carries a significant potential for serious adverse effects. Ototoxicity from cisplatin treatment is an important dose-limiting toxicity that manifests as bilateral, progressive, irreversible, dose-dependent sensorineural hearing loss, ear pain, tinnitus, and vestibular dysfunction. Despite the recent approval of sodium thiosulphate for the prevention of cisplatin-induced hearing loss (CIHL) in pediatric patients, structured prevention programs are not routinely implemented in most hospitals, and reducing platinum-induced ototoxicity in adults remains an important clinical problem without established treatment options.
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