Fetal dose evaluation for body CT examinations of pregnant patients during all stages of pregnancy.

Purpose: CTDI-to-fetal-dose coefficients from Monte Carlo simulations are useful for fetal dose evaluations, but the available data is limited to the fetus being completely inside the abdominopelvic scan range. Whereas in a chest examination, the fetus is completely outside the scan range. In an abdominal examination, the fetus after 16 gestational weeks is partly in the scan region, and an earlier fetus is completely outside of it. This work proposes a practical approach to evaluate fetal dose for pregnant patients undergoing body CT examinations, without using Monte Carlo simulation.

Methods: The proposed method was based on the z-axis dose profile computed for a CT examination, considering CTDI, scan range, mA, and maternal WED (water equivalent diameter) at the fetus centroid. Fetal average dose was calculated over the fetus z-axis coverage. For validation, we considered a reference dataset of 24 pregnant patients, each underwent two abdominopelvic examinations (fixed mA, tube current modulation). WED was 30.1 ± 3.3 (25.3-35.6) cm [mean(range)]. Gestational age was <5 weeks for one patient, and 20.3 ± 9.1 (5-35.9) weeks for the others. Fetal depth (from the anterior skin surface to the most anterior part of fetus) was 6.1 ± 2.1 (2.5-10.9) cm. We further considered three whole-body models of a pregnant patient (gestational age, 3, 6, 9 months; weight, 62-73 kg) undergoing chest, abdominal, and abdominopelvic examinations (fixed mA). For the patients and models, profile-based fetal dose calculations were compared with the results of Monte Carlo simulations. Statistical software (R, version 3.5.1) was used to determine the mean and 95th percentile.

Results: The fetal dose difference between profile-based evaluations and Monte Carlo simulations was (5.9 ± 3.8)% for 24 fixed-mA examinations, (5.8 ± 4.6)% for 24 tube current modulated examinations, and (8.8 ± 5.9)% for the whole-body models in three scan ranges.

Conclusions: Profile-based fetal dose calculations can be performed for patients in body CT, considering maternal size, fetus size and location, and whether fetus is completely inside, partly inside, or outside scan ranges.