Development of Diverse Range of Biologically Relevant Carbohydrate-Containing Molecules: Twenty Years of Our Journey*.

Chem Rec

Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, U.P.-221005, India.

Published: November 2021

There is an increasing demand for significant amount of carbohydrate-containing molecules owing to their complete chemical, biological, and pharmacological investigations to better understand their role in many important biological events. Clinical studies of a wide range of simple carbohydrates or their derivatives, glycohybrids, glycoconjugates, and neoglycoconjugates have been conducted worldwide for the successful treatment of various frontline diseases. Herein, a brief perspective of carbohydrate-based molecular scaffolding and my experience during the last 20 years in the area of synthetic carbohydrate chemistry, mainly for their impact in drug discovery & development, is presented.

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Source
http://dx.doi.org/10.1002/tcr.202100058DOI Listing

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