Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485672PMC
http://dx.doi.org/10.3324/haematol.2020.276634DOI Listing

Publication Analysis

Top Keywords

inclusion short
4
short hairpin
4
hairpin rna
4
rna targeting
4
targeting β-globin
4
β-globin expressing
4
expressing vector
4
vector allows
4
allows concurrent
4
concurrent synthesis
4

Similar Publications

Background: Cost-utility analyses commonly use two primary methods to value productivity: the human capital approach (HCA) and the friction cost approach (FCA). Another less frequently used method is the willingness-to-pay (WTP) approach, which estimates the monetary value individuals assign to avoiding an illness. In the context of foodborne illnesses (FBI), productivity loss represents one of the most significant economic impacts, particularly in developed nations.

View Article and Find Full Text PDF

Digital hate is typically targeted toward individuals or groups based on distinct attributes. Despite numerous studies on targets of digital hate, there is a lack of a systematic meta-perspective on targets' perceptions of digital hate. Therefore, this scoping review aims to assess available definitions and characteristics of targets, consequences of digital hate together with targets' reactions and coping strategies, dominant methodologies, and identified future outlooks of digital hate victimization research.

View Article and Find Full Text PDF

Objective: This meta-analysis evaluates the comparative efficacy of lateral unicompartmental arthroplasty (UKA) versus medial UKA in treating unicompartmental knee osteoarthritis (KOA).

Methods: We systematically searched Cochrane, PubMed, Embase, and Web of Science databases from January 2000 to September 2024. Literature screening, quality assessment, and data extraction were conducted based on predefined inclusion and exclusion criteria.

View Article and Find Full Text PDF

Background: In the intensive care unit (ICU), the incidence of iron-deficiency anemia (IDA) is relatively high and is associated with various adverse clinical outcomes. Therefore, it is crucial to identify simple and practical indicators to assess the mortality risk in ICU patients with IDA. This study aims to investigate the relationship between the Neutrophil Percentage-to-Albumin Ratio (NPAR) levels in patients with IDA in the ICU and their all-cause mortality at 30 and 365 days.

View Article and Find Full Text PDF

Background: NSAIDs are commonly used as first line therapy in chronic nonbacterial osteomyelitis (CNO) but are not effective for all patients. The objective of this study was to identify clinical variables associated with NSAID monotherapy response versus requiring second-line medication in a single-center cohort of patients with CNO.

Methods: The charts of children with CNO who attended a CNO clinic at a quaternary care center between 1/1/05 and 7/31/21 were retrospectively reviewed.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!