Purpose: This systematic review characterizes the safety and efficacy of total knee arthroplasty (TKA) in end stage renal disease (ESRD) patients due to the unique challenges they face.
Results: The cumulative complication rate for 3684 patients on dialysis for ESRD after primary TKA was 25%(N = 925/3702), with incidence rates of 2.5%(N = 92/3702) for periprosthetic joint infection, 3.7%(N = 71/1895) for reoperations, and 2.5%(N = 90/3578) for mortality.
Conclusion: Patients on dialysis for ESRD face significant mortality rates after primary TKA, in addition to other major complications. Careful counseling regarding risks and benefits should be provided prior to TKA in this population.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144102 | PMC |
http://dx.doi.org/10.1016/j.jor.2021.05.025 | DOI Listing |
J Am Acad Orthop Surg
January 2025
From the Department of Orthopaedic Surgery, The George Washington University School of Medicine and Health Sciences, Washington, DC (Raftis, Zhao and Gu), the Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD (Dr. Agarwal, Dr. Harris, Dr. Kurian, and Thakkar), and the Department of Orthopaedic Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA (Golladay).
Introduction: Lower estimated glomerular filtration rate (eGFR) in patients who have chronic kidney disease (CKD) is associated with increased risk of complications following total knee arthroplasty (TKA). However, there is a lack of literature that identifies eGFR levels those are associated with notable differences in risk of these complications. The purpose of this study was to create eGFR strata for CKD patients that are associated with varying risks of 90-day major complications following TKA.
View Article and Find Full Text PDFJ Am Acad Orthop Surg
January 2025
From the Department of Orthopaedic Surgery, Kaiser Permanente San Diego Medical Center, San Diego, CA (Horan), the Department of Orthopaedic Surgery, Summit Orthopedics, Eagan, MN (Baer), Shiley Center for Orthopaedic Research and Education (SCORE) at Scripps Clinic, La Jolla, CA (Shah), Georgetown University School of Medicine, Washington, DC (Shah), and the Department of Orthopaedic Surgery, Scripps Clinic, La Jolla, CA (Wilde, Copp, and Bugbee).
Background: Total knee arthroplasty (TKA) is a well-established treatment option for advanced knee osteoarthritis, yet some patients remain unsatisfied after surgery. Evaluation of various psychosocial parameters may improve patient optimization and outcomes. The primary aim was to assess whether preoperative resilience remained stable and influenced decision regret postoperatively while the secondary aim was to evaluate its correlation with joint-specific and global health patient-reported outcome measures.
View Article and Find Full Text PDFJMIR Form Res
January 2025
Division of Human Nutrition and Health, Wageningen University & Research, Stippeneng 4, PO Box 17, Wageningen, 6700 AA, Netherlands.
Background: The lifestyle intervention ProMuscle, which combines resistance exercise and an increased protein intake, was effective in improving muscle strength, muscle mass, and physical functioning in older adults. However, due to a growing shortage of health care professionals, the rapidly growing aging population cannot be personally guided in the future. Therefore, Uni2Move, a scalable web-based variant of ProMuscle, was designed to reach larger groups of older adults without putting additional burden on health care professionals.
View Article and Find Full Text PDFJ Clin Orthop Trauma
March 2025
Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences, Nitte (Deemed to be University), Mangaluru, India.
Background: The effectiveness of intra-articular platelet-rich plasma (IA-PRP) injections for managing pain in knee osteoarthritis (KOA) remains inconsistent. Therefore, this study aimed to systematically review randomized controlled trials (RCTs) assessing the efficacy of IA-PRP.
Methods: A total of 21 studies meeting the inclusion criteria were selected from various scientific databases, all of which compared PRP to either a placebo or an active comparator, such as corticosteroids (CS), in the treatment of KOA.
Background: Postoperative cognitive dysfunction (POCD) is a common complication after total knee arthroplasty (TKA), impacting recovery and quality of life. This study aims to investigate central sensitization (CS) as an independent risk factor for POCD to improve preoperative screening and postoperative interventions.
Methods: A retrospective analysis was conducted on 142 TKA patients from January 2020 to May 2024 across three hospitals.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!