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AcfA Regulates the Virulence and Cell Envelope Stress Response of .
Microorganisms
December 2024
School of Food Science and Engineering, Shaanxi University of Science & Technology, No. 6 Xuefu Road, Xi'an 710021, China.
is a ubiquitous inhabitant of estuarine and marine environments that causes vibriosis in aquatic animals and food poisoning in humans. Accessory colonizing factor (ACF) is employed by to assist in the colonization and invasion of host cells leading to subsequent illnesses. In this work, Δ, an in-frame deletion mutant strain lacking the 4th to the 645th nucleotides of the open reading frame (ORF) of the gene, and the complementary strain were constructed to decipher the function of AcfA in .
View Article and Find Full Text PDFSilver-Treated Sutures for the Prevention of Biofilm-Associated Surgical Site Infections.
Antibiotics (Basel)
January 2025
Department of Experimental Medicine, University of Salento, Via Monteroni, 73100 Lecce, Italy.
Background/objectives: The huge concerns associated with biofilm-related infections in surgical procedures, along with the antibiotic resistance demonstrated by an increasing number of bacteria, have highlighted the need for alternative and effective prevention approaches. The aim of this research was to develop novel antimicrobial coatings on surgical sutures for the prevention of surgical site infections through nanotechnology-based methods.
Results: The results demonstrated that although very low amounts of silver precursor were adopted for the treatments, the silver coating was effective against and antibiotic-resistant in reducing the potential risk of infection.
Tracheobronchitis in Noncritically Ill Children With Tracheostomy: Can Quantitative Tracheal Cultures Assist in the Management?
Pediatr Pulmonol
January 2025
Department of Pediatric Internal Medicine, La Paz University Hospital, Madrid, Spain.
Background And Objectives: Bacteria in tracheal aspirate samples from children with tracheostomy can indicate infection or colonization. Our study aimed to determine whether bacterial counts > 10 or > 10 CFU (colony forming units)/mL are more frequently associated with tracheobronchitis. Additionally, we aimed to examine the association between bacterial count and variables distinguishing colonization from infection in tracheobronchitis, along with clinical severity indicators.
View Article and Find Full Text PDFCo-culture of Helicobacter pylori with oral microorganisms in human saliva.
Clin Oral Investig
January 2025
Department of Operative Dentistry and Periodontology, Center for Dental Medicine, Medical Center- University of Freiburg, Faculty of Medicine, University of Freiburg, University of Freiburg, Freiburg, Germany.
Objective: Helicobacter pylori is known for colonizing the gastric mucosa and instigating severe upper gastrointestinal diseases such as gastritis, gastroduodenal ulcers, and gastric cancer. To date, there is no data available on the oral cavity as transmission site, whether H. pylori can survive in the oral cavity or in human saliva.
View Article and Find Full Text PDFImpact of an electronic surveillance system on compliance with isolation precaution measures: an interrupted time series study.
Infect Dis (Lond)
January 2025
Inserm, INSPIIRE, Université de Lorraine, Vandœuvre-lès-Nancy, France.
Background: Electronic surveillance systems (ESSs) may assist infection prevention and control (IPC) teams in detecting and monitoring patients infected or colonised by pathogens to prevent healthcare-associated infections. We aimed to assess the impact of implementing an ESS on compliance with isolation precaution measures for bacterial infections or colonizations.
Methods: A quasi-experimental before-after study was conducted using interrupted time series analysis from 1 March 2018 to 31 July 2024 at the University Hospital of Nancy (France).
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