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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1033097 | PMC |
| http://dx.doi.org/10.1136/jnnp.51.5.740-a | DOI Listing |
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Contact heat evoked potentials reveal distinct patterns of spinal cord impairment in degenerative cervical myelopathy beyond MRI lesions.
Eur J Neurol
January 2025
Spinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Background: Magnetic resonance imaging may suggest spinal cord compression and structural lesions in degenerative cervical myelopathy (DCM) but cannot reveal functional impairments in spinal pathways. We aimed to assess the value of contact heat evoked potentials (CHEPs) in addition to MRI and hypothesized that abnormal CHEPs may be evident in DCM independent of MR-lesions and are related to dynamic mechanical cord stress.
Methods: Individuals with DCM underwent neurologic examination including segmental sensory (pinprick, light touch) and motor testing.
Neuropathic pain relief and altered brain networks after dorsal root entry zone microcoagulation in patients with spinal cord injury.
Brain Commun
November 2024
Spaulding Neuroimaging Laboratory, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA 02129, USA.
Article Synopsis
- Spinal cord injury (SCI) below-level neuropathic pain is challenging to treat, but surgical lesions in the spinal cord’s dorsal root entry zone (DREZ) can target pain sources effectively.
- A study with eight patients showed significant improvement in pain relief after neuroelectrically guided DREZ microcoagulation surgery, with some experiencing long-term relief for over a year.
- Changes in brain connectivity were observed post-surgery, indicating that the procedure not only alleviated pain but also normalized brain function related to sensory and motor processing.
Midline sacral meningeal cysts: Neurophysiology abnormalities and their correlation with pelvic sensory and visceral symptoms.
Eur J Neurol
January 2025
Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, London, UK.
Article Synopsis
- MSMCs are typically asymptomatic cysts but can lead to symptoms like urinary issues and pain in some patients, prompting this study.
- The research involved a thorough assessment of patients with symptomatic MSMCs, utilizing questionnaires and neurophysiology tests to understand the impact on nerve function.
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Intra-epidermal electrically evoked potentials are sensitive to detect degenerative cervical myelopathy suggesting their spinothalamic propagation.
Clin Neurophysiol
November 2024
Spinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland. Electronic address:
Objective: Degenerative cervical myelopathy (DCM) is a centromedullary spinal cord disorder mainly affecting crossing fibers. While contact heat evoked potentials (CHEPs) are sensitive in detecting DCM by testing spinothalamic integrity, somatosensory evoked potentials (dSSEPs) show unaffected dorsal column conduction. Intra-epidermal electrically evoked potentials (IEEPs) have unknown spinal propagation after noxious stimulation.
View Article and Find Full Text PDFSomatosensory Mapping Using a Novel Sensory Discrimination Task: Technical Note.
Oper Neurosurg (Hagerstown)
September 2024
Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA.
Background And Objectives: Although diffuse gliomas in the primary somatosensory cortex (S1) are often considered resectable, gliomas in the primary motor cortex require motor mapping to preserve motor function. Recent evidence indicates that some somatosensory cortex neurons may trigger motor responses, necessitating refined somatosensory mapping techniques.
Methods: Using piezoelectric tactile stimulators on patients' faces and hands, we delivered 25 Hz vibrations and prompted patients to discriminate between dermatomes.
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