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Topological analysis and predictive modeling of amino acid structures with implications for bioinformatics and structural biology.
Sci Rep
January 2025
Department of Mathematics, College of Natural and Computational Sciences, Wollega University, Nekemte, Ethiopia.
Amino acids, as the fundamental constituents of proteins and enzymes, play a vital role in various biological processes. Amino acids such as histidine, cysteine, and methionine are known to coordinate with metal ions in proteins and enzymes, playing critical roles in their structure and function. In metalloproteins, metal ions are often coordinated by specific amino acid residues, contributing to the protein's stability and catalytic activity.
View Article and Find Full Text PDFSince 1979, The Belmont Report has served as a guidebook for ensuring that basic standards for ethical research are upheld. The Belmont Report calls for special protections of vulnerable research participants, such as people who are incarcerated and economically and educationally disadvantaged individuals who are deemed susceptible to exploitation. With a growing focus on health equity and community-engaged approaches in health equity research, efforts to involve vulnerable participants are increasing.
View Article and Find Full Text PDFHealth differences between rural and non-rural Texas counties based on 2023 County Health Rankings.
BMC Health Serv Res
January 2025
Translational Health Research Center, Texas State University, 601 University Drive, San Marcos, TX, 78666, USA.
Background: Place matters for health. In Texas, growing rural populations face a variety of structural, social, and economic disparities that position them for potentially worse health outcomes. The current study contributes to understanding rural health disparities in a state-specific context.
View Article and Find Full Text PDFWhat do medical students think about conscientious objection? A cross-sectional study from Turkey.
BMC Med Educ
January 2025
Honors College, University of Houston, Houston, USA.
Background: Physicians' refusal to perform medical procedures that they deem contrary to their conscience may threaten basic human rights and public health. This study aims to investigate the thoughts and attitudes of future physicians on conscientious objection (CO) and thus contribute to the discussions from a country more heavily influenced by Eastern values.
Methods: A cross-sectional multi-center study was conducted among medical students country-wide, where 2,188 medical students participated via an online survey.
Cross-cultural adaptation and validation of Dysphagia Handicap Index in Bangladesh.
J Patient Rep Outcomes
January 2025
Department of SLT, Bangladesh Health Professions Institute (BHPI), CRP, Dhaka, Bangladesh.
The Dysphagia Handicap Index (DHI) is commonly utilized for evaluating how dysphagia impacts the quality of life (QoL) of patients across physical, functional, and emotional dimensions. The primary aim of the research was to linguistically validate and culturally adapt the DHI to the Bangla version. A cross-sectional study design was chosen, with Beaton's protocol as the guiding framework for validating and adapting the DHI.
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