Three statistical methods: Bayesian, randomized data binning and Maximum Entropy Method (MEM) are described and applied in the analysis of US radon data taken from the US registry. Two confounding factors-elevation of inhabited dwellings, and UVB (ultra-violet B) radiation exposure-were considered to be most correlated with the frequency of lung cancer occurrence. MEM was found to be particularly useful in extracting meaningful results from epidemiology data containing such confounding factors. In model testing, MEM proved to be more effective than the least-squares method (even via Bayesian analysis) or multi-parameter analysis, routinely applied in epidemiology. Our analysis of the available residential radon epidemiology data consistently demonstrates that the relative number of lung cancers decreases with increasing radon concentrations up to about 200 Bq/m, also decreasing with increasing altitude at which inhabitants live. Correlation between UVB intensity and lung cancer has also been demonstrated.
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http://dx.doi.org/10.1177/15593258211009337 | DOI Listing |
JAMA Netw Open
January 2025
Department of Obstetrics and Gynecology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York.
Importance: Understanding environmental risk factors for gestational diabetes (GD) is crucial for developing preventive strategies and improving pregnancy outcomes.
Objective: To examine the association of county-level radon exposure with GD risk in pregnant individuals.
Design, Setting, And Participants: This multicenter, population-based cohort study used data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b) cohort, which recruited nulliparous pregnant participants from 8 US clinical centers between October 2010 and September 2013.
Sci Total Environ
January 2025
Key Laboratory of Surficial Geochemistry, Ministry of Education, School of Earth Sciences and Engineering, Nanjing University, Nanjing 210023, China.
Lake eutrophication driven by excessive nutrient inputs has become a global issue, but the potential impact of lacustrine groundwater discharge (LGD) as a nutrient source on lake eutrophication remains largely unknown. This study assessed the contribution of LGD-derived nutrient loads and revealed their potential impact on lake eutrophication in Taihu Lake, a typical large shallow and eutrophic lake in China, based on the segmented radon mass balance model and nutrient data. The total LGD flux was estimated to be 6.
View Article and Find Full Text PDFPhys Med Biol
January 2025
Department of Electrical and Electronic Engineering, The University of Hong Kong, Chow Yei Ching 506, Hong Kong, 999077, HONG KONG.
. The propagation speed of a shear wave, whether externally or internally induced, in biological tissues is directly linked to the tissue's stiffness. The group shear wave speed (SWS) can be estimated using a class of time-of-flight (TOF) methods in the time-domain or phase speed-based methods in the frequency domain.
View Article and Find Full Text PDFEnviron Geochem Health
January 2025
Nuclear Technology Research and Development Center, Thailand Institute of Nuclear Technology, Nakhon Nayok, 26120, Thailand.
The present study aimed to investigate the hydrogeochemical patterns and contamination of the radiogeology, especially radon activity, related to geothermal aquifer properties and to perform a risk assessment of annual effective doses covering all hydrothermal spring attractions in Southern Thailand. Radon is an established lung carcinogen; especially longer term exposure to radioactive radon through inhalation could be a cause of lung cancer risk. Altogether 22 hydrothermal spring samples were collected from the six hydrothermal provinces in Southern Thailand in early November of 2023.
View Article and Find Full Text PDFFront Public Health
December 2024
School of Preventive Medicine, Shandong First Medical University (Institute of Radiation Medicine, Shandong Academy of Medical Sciences), Jinan, Shandong, China.
Background: Radon, a colorless and odorless radioactive gas, poses serious health risks. It is the second leading cause of lung cancer and notably increases lung cancer risk in smokers. Although previous epidemiological studies have mainly examined lung cancer rates in miners, the effects of radon on genomic stability and its molecular mechanisms are not well understood.
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