Context: Stroke caused 6.7 million deaths worldwide in 2013. In India, the cumulated incidence of stroke was 105-152/100,000 persons per year in last decade. Dearth of data on predictors of stroke subtype and severity in India lead to this study.
Aims: (1) To categorize presenting stroke patients by subtype and severity. (2) To establish association of risk factors with above. (3) To predict subtype and severity by risk factors.
Settings And Design: Hospital-based cross-sectional analytic, retrospective study.
Subjects And Methods: A predesigned, pretested, semi-structured questionnaire with standard tool (National Institute of Health Stroke Scale Score), informed consent after prior approval of institutional ethics and research committees.
Statistical Analysis Used: Percentages, proportions, Chi-square trends, linear regression, independent -test, and analysis of variance (ANOVA).
Results: Mean age of 102 patients was 62.1 (±12.8 years). Stroke subtype associated with socioeconomic status (χ = 6.38775, = 0.0115) and stroke severity (χ = 18.98, = 0) and stroke severity associated with stroke subtype (χ = 9.79366, = 0.0018). Stroke subtype could be predicted by stroke severity and stroke severity by subtype, sex, and dyslipidemia (regression models). Independent -test revealed excessive alcohol intake was a significant predictor and one-way ANOVA revealed education was a significant predictor of severe stroke.
Conclusions: Stroke subtype is significantly associated with higher socioeconomic status and severe stroke. Stroke severity is significantly associated with hemorrhagic stroke. Stroke subtype, sex, dyslipidemia, alcohol intake, and education may act as predictors of stroke severity.
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http://dx.doi.org/10.4103/ijcm.IJCM_465_20 | DOI Listing |
CNS Neurosci Ther
January 2025
Department of Research, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
Background: Stroke remains a leading cause of mortality and disability among adults. Given the restricted therapeutic window for intravascular interventions and neuroprotection during the acute phase, there has been a growing focus on tissue repair and functional recovery in the subacute and chronic phases after stroke. The pro-inflammatory microglial polarization occurs in subacute and chronic phases after stroke and may represent therapeutic targets for stroke recovery.
View Article and Find Full Text PDFNiger Med J
January 2025
Department of Radiology, Usmanu Danfodiyo University Teaching Hospital Sokoto, Nigeria.
Background: Stroke remains one of the major non-communicable public health disease conditions with resultant high morbidity and mortality. Neuroimaging in the form of Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) is adjudged to be the most reliable and efficient method of accurately diagnosing stroke and ruling out differentials. However, in view of cost implication and non-availability, a clinical scoring system known as the Siriraj Stroke Score (SSS) was developed to clinically differentiate stroke types, especially in resource-limited settings.
View Article and Find Full Text PDFClin Neurol Neurosurg
January 2025
Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, China. Electronic address:
Objective: The prevalence of ischemic stroke in young adults has increased dramatically. However, factors associated with prognosis in this cohort have not been well studied. This study primary aimed to construct and validate a nomogram for predicting stroke recurrence and to achieve risk stratification of young adults after acute ischemic stroke (AIS).
View Article and Find Full Text PDFJ Stroke Cerebrovasc Dis
January 2025
Shandong First Medical University, Jinan 250117, Shandong, China; Department of Neurosurgery, Liaocheng People's Hospital, Liaocheng 252000, Shangdong, China. Electronic address:
Background: Previous observational studies have suggested a potential association between heart rate variability (HRV) and cerebrovascular disease. However, a causal relationship between the two has not yet been established.
Aims: The objective of this study was to determine the causal relationship between heart rate variability (HRV) and stroke through a two-sample Mendelian randomization analysis.
Genes (Basel)
January 2025
Department of Stroke and Cerebrovascular Diseases, University of Tsukuba Hospital, Tsukuba 305-8576, Japan.
Background/objectives: Recent advances in stroke genetics have substantially enhanced our understanding of the complex genetic architecture underlying cerebral infarction and other stroke subtypes. As knowledge in this field expands, healthcare providers must remain informed about these latest developments. This review aims to provide a comprehensive overview of recent advances in stroke genetics, with a focus on cerebral infarction, and discuss their potential impact on patient care and future research directions.
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