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Maternal education and prenatal smoking associations with adolescent executive function are substantially confounded by genetics.
Dev Psychol
January 2025
School of Philosophy, Psychology, and Language Sciences, University of Edinburgh.
Twin studies have suggested extremely high estimates of heritability for adolescent executive function, with no substantial contributions from shared environment. However, developmental psychology research has found significant correlations between executive function outcomes and elements of the environment that would be shared in twins. It is unclear whether these seemingly contradictory findings are best explained by genetic confounding in developmental studies or limitations in twin studies, which can potentially underestimate shared environment.
View Article and Find Full Text PDFBackground: Several studies evaluated peripheral and cerebrospinal fluid (CSF) mtDNA as a putative biomarker in neurodegenerative diseases, often yielding inconsistent findings. We systematically reviewed the current evidence assessing blood and CSF mtDNA levels and variant burden in Parkinson's disease (PD), Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS). Multiple sclerosis (MS) was also included as a paradigm of chronic neuroinflammation-driven neurodegeneration.
View Article and Find Full Text PDFHormonal Implications of SARS-CoV-2: A Review of Endocrine Disruptions.
Scientifica (Cairo)
January 2025
Department of Natural Sciences, Akhmet Baitursynuly Kostanay Regional University, Kostanay, Kazakhstan.
To improve medical care and rehabilitation algorithms for patients affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is important to evaluate and summarize the available data on the effect of coronavirus infection (COVID-19) on the endocrine system. The purpose of this review was to study the effect of COVID-19 on the endocrine system. The scientific novelty of this study is the evaluation of the effect of coronavirus infection on the endocrine system and the potential effect of hormones on susceptibility to COVID-19.
View Article and Find Full Text PDFThe Relationship Between Weight Indices and Blood Levels of Immunosuppressive Drugs in Renal Transplant Recipients.
Iran J Pharm Res
September 2024
Department of Clinical Pharmacy and Pharmacy Practice, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Calcineurin inhibitors and mammalian target of rapamycin (mTOR) inhibitors are essential for maintaining transplanted organs. However, determining the appropriate dosage and predicting blood concentrations of these drugs based solely on net body weight may be inadequate. Previous studies have presented contradictory results regarding the impact of obesity on drug concentrations and transplant success.
View Article and Find Full Text PDFEncountering children with suspected neurodevelopmental disorders in Child Health Services: Swedish nurses' experiences.
J Pediatr Nurs
January 2025
Department of Health Sciences, Lund University, Sölvegatan 19, Sweden. Electronic address:
Purpose: To describe nurses' experiences encountering children with suspected neurodevelopmental disorders in Child Health Services.
Design And Methods: This qualitative inductive study was conducted in Sweden. Twenty nurses were interviewed individually on a virtual platform using a semi-structured interview guide with open-ended and explorative questions.
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