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Hackathons aim to solve problems in a selected field by bringing together people from multiple domains and combining their expertise. Global surgery is an emerging field with a huge burden of disease and massive implications for bettering health care. In this study, we describe the first Global Surgery Hackathon held in Pakistan and analyze the impacts of the hack and post-hack incubation. This research study used data collected from a Hackathon held at the Aga Khan University (AKU) in Karachi, Pakistan, and progress from the post-hack incubation teams. Data were collected from applications, from sign-in attendance, via evaluation forms, and milestone tracking of the incubation teams. A list of factors such as sectors addressed by winning projects and grants received was made. The evaluations provided by the participants were positive, with mean scores of 4.00 (SD = .78) out of 5 on a Likert scale. Pitches made (n = 69, 68%) by the 109 participants were sorted into 5 categories: workplace, access, quality, safety, and design. Fifteen teams were formed, out of which 5 were accepted for incubation. All teams had a minimum viable product at the one-year mark. Hackathons are a reliable way to come up with effective solutions for targeted problems in various areas of health care and using the methodology of a Hackathon, a pool of low-cost, innovative solutions can be generated. These solutions can definitely impact health outcomes, especially for the field of global surgery. Further statistics should be collected to affirm the incubated solutions' impact.
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http://dx.doi.org/10.1177/15533506211018619 | DOI Listing |
Ultrasound Med Biol
March 2025
Midwest Fetal Care Center, Children's Minnesota, Minneapolis, MN, USA; Children's Heart Clinic, Children's Minnesota, Minneapolis, MN, USA.
Objective: No clinical standard exists for intraoperative fetal cardiac monitoring during maternal-fetal surgery for fetal myelomeningocele (fMMC). This pilot study explores the feasibility of using speckle tracking echocardiography (STE)-derived functional measurements to characterize cardiac performance throughout fetoscopic fMMC and compares these measures with other common intraoperative cardiac function parameters.
Methods: Continuous fetal echocardiography was performed during fetoscopic fMMC repair with fetal heart rate assessment every 2 minutes and a 4-chamber cine clip and mitral and tricuspid Doppler inflow patterns captured every 5 minutes.
BMJ Glob Health
March 2025
Family Medicine and Community Health, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Purpose: This study longitudinally assessed the quality of life (QoL) in patients who completed chemoradiation (CRT) for cervical cancer in Botswana and compared the QoL for those living with and without HIV infection.
Methods: Patients with cervical cancer recommended for curative CRT were enrolled from August 2016 to February 2020. The European Organisation for Research and Treatment of Cancer Core Quality-of-Life (QLQ-C30) and cervical cancer-specific (QLQ-Cx24) questionnaires, translated into Setswana, were used to assess the QoL of patients prior to treatment (baseline), at the end of treatment (EOT) and in 3 month intervals post-treatment for 2 years, and statistical analyses were performed.
J Thromb Haemost
March 2025
Institute for Clinical and Translational Research, Johns Hopkins All Children's, St. Petersburg, FL, USA; Cancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, FL, USA; Cancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, FL, USA.
Background: Data on the characteristics and antithrombotic treatments of venous thromboembolism (VTE) among children with congenital heart disease (CHD) undergoing cardiac surgery are limited.
Objective: (s): To evaluate the features and rates of recurrent thromboembolism in real-world experience, using a global multicenter dataset.
Methods: We queried the TriNetX global electronic health record (EHR)-derived real-world data research platform for patients <18 years of age who underwent cardiac surgery for CHD with a diagnosis of VTE within 1 year of surgery.
Ann Vasc Surg
March 2025
University of Ibadan College of Medicine, Ibadan, Nigeria.
Background: With Africa's population growth and an epidemiological shift from communicable to non-communicable diseases, there is an urgent need to expand vascular surgery capacity across the continent. Despite a high disease burden, Sub-Saharan Africa contributes less than 1% of the global surgical research, with significant challenges in surgical infrastructure, access to consumables, and limited research output. This study assesses the publication output of African authors in the top five vascular surgery journals and explores trends in African vascular research.
View Article and Find Full Text PDFEur J Cancer
March 2025
Mount Sinai Health System, New York, NY, USA. Electronic address:
Lung cancer screening implementation has led to expanded imaging of the chest in older, tobacco-exposed populations. Growing numbers of screening cases are also found to have CT-detectable emphysema or elevated levels of coronary calcium, indicating the presence of coronary artery disease. Early interventions based on these additional findings, especially with coronary calcium, are emerging and follow established protocols.
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