The rate of spread of the global pandemic calls for much attention from the empirical literature. The limitation of extant literature in assessing a comprehensive COVID-19 portfolio that accounts for complexities in the spread and containment of the virus underscores this study. We investigate the effect of city-to-city air pollutant species, meteorological conditions, underlying health conditions, socio-economic and demographic factors on COVID-19 health outcomes. We utilize a panel estimation of 615 cities in 6 continents from January 1 to June 11, 2020. While social distancing measures, movement restrictions and lockdown are reported to have improved environmental quality, we show that ambient PM remains unhealthy and above the acceptable threshold in several countries. Our empirical assessment shows that while ambient PM, nitrogen dioxide, ozone, pressure, dew, Windgust, and windspeed increase the spread of COVID-19, high relative humidity and ambient temperature have mitigation effect on COVID-19, hence, decreases the number of confirmed cases. We report 66.3% of countries projected to experience a second wave of COVID-19 if government stringency and safety protocols are not enhanced. By extension, our assessments demonstrate that several factors namely underlying health conditions, meteorological, air pollution, health system quality, socio-economic and demographics spur the reproduction effect of COVID-19 across countries. Our study highlights the importance of government stringency in containing the spread of COVID-19 and its impacts.
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http://dx.doi.org/10.1016/j.scitotenv.2021.146394 | DOI Listing |
Eur J Pediatr
January 2025
Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Unlabelled: Klinefelter syndrome (KS) is the most common sex chromosomal aneuploidy in males (47,XXY karyotype in 80-90% of cases), primarily characterized by hypergonadotropic hypogonadism and infertility. It encompasses a broad phenotypic spectrum, leading to variability in neurocognitive and psychosocial outcomes among affected individuals. Despite the recognized correlation between KS and various neuropsychiatric conditions, studies investigating potential sleep disorders, particularly in pediatric subjects, are lacking.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Clinical Medicine, Fujian Medical University, Fuzhou, 350000, China.
Acute lung injury (ALI) is a severe inflammatory condition of the respiratory system, associated with high morbidity and mortality. This study investigates the therapeutic potential of tocilizumab (TZ), an IL-6 receptor inhibitor, in mitigating lipopolysaccharide (LPS)-induced ALI by modulating the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) pathway. An ALI model was established using LPS induction.
View Article and Find Full Text PDFChilds Nerv Syst
January 2025
Department of Global Health, Faculty of Health Sciences, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.
Background: A giant encephalocele associated with Chiari malformation is a rare congenital anomaly from a cephalad neural tube defect. Early prenatal diagnosis and parental counseling are essential; as early surgical intervention can improve outcomes.
Methods: Between 2010 and 2023, twenty-seven newborns out of 43,815 delivered at our institution were diagnosed with encephaloceles, including seven cases of giant encephalocele associated with Chiari malformation type III.
Geroscience
January 2025
Dept. of Bioinformatics, Semmelweis University, 1094, Budapest, Hungary.
Age-related cognitive impairment and dementia pose a significant global health, social, and economic challenge. While Alzheimer's disease (AD) has historically been viewed as the leading cause of dementia, recent evidence reveals the considerable impact of vascular cognitive impairment and dementia (VCID), which now accounts for nearly half of all dementia cases. The Mediterranean diet-characterized by high consumption of fruits, vegetables, whole grains, fish, and olive oil-has been widely recognized for its cardiovascular benefits and may also reduce the risk of cognitive decline and dementia.
View Article and Find Full Text PDFRadiol Phys Technol
January 2025
Department of Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, 7-2-10 Higashi-ogu, Arakawa, Tokyo, 116-8551, Japan.
In plain radiography, scattered X-ray correction processing (Virtual Grid: VG) is used to estimate and correct scattered rays in images. We developed an objective evaluation system for bedside chest X-ray images using VG and investigated its usefulness. First, we trained the blind/referenceless image spatial quality evaluator (BRISQUE) on 200 images obtained by portable chest radiography.
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