Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143422 | PMC |
| http://dx.doi.org/10.1371/journal.pntd.0009402 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), remains a significant threat to global public health. Immunopathological damage plays a role in driving pneumonia, acute respiratory distress syndrome (ARDS), and multiorgan failure in severe COVID-19. Therefore, dissecting the pulmonary immune response to SARS-CoV-2 infection is critical to understand disease pathogenesis and identify immune pathways targetable by therapeutic intervention.
View Article and Find Full Text PDFCOVID-19 vaccination survey and anti-SARS-CoV-2 IgG responses in a human cohort from -endemic villages in Mayuge District, Uganda: a cross-sectional study.
Front Public Health
December 2024
Molecular Parasitology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Article Synopsis
- The COVID-19 pandemic has had severe health and economic impacts globally, with vaccination being crucial for control, especially in regions with high rates of helminth infections, which could affect vaccine responses.
- A study in Uganda surveyed 450 individuals to assess helminth prevalence and COVID-19 vaccine responses; results showed high infection rates of schistosomiasis (36.4%) and hookworms (36.9%), with 93.14% vaccination coverage among a smaller group interviewed.
- Despite widespread vaccination, a significant portion of those vaccinated had low anti-S1 IgG antibody levels, indicating that helminth infections might reduce vaccine efficacy among individuals with moderate to heavy infections.
Formulation and Ex Vivo Evaluation of Ivermectin Within Different Nano-Drug Delivery Vehicles for Transdermal Drug Delivery.
Pharmaceutics
November 2024
Centre of Excellence for Pharmaceutical Sciences (Pharmacen™), North-West University, Potchefstroom 2531, South Africa.
Article Synopsis
- * Despite its beneficial qualities, ivermectin has poor water solubility which limits its effectiveness when taken orally, prompting researchers to explore transdermal delivery methods using various nano-formulations.
- * The study found that ivermectin-loaded nanoparticles successfully released the drug through the skin with minimal cytotoxicity, indicating that the choice of delivery vehicle significantly affects the drug's absorption and overall therapeutic potential.
Ascaris in infected pancreatic pancreatic necrosum: a case report of an intraoperative surprise.
Ann Med Surg (Lond)
November 2024
Department of Gastrointestinal Surgery, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Introduction And Importance: Ascariasis lumbricoides is a common gastrointestinal tract helminthic disease in developing countries and is also a cause of hepatobiliary and pancreatic disease in endemic areas of the world. Involvement of the pancreatic duct by worms and associated pancreatitis is less common than the hepatic and biliary involvement.
Case Presentation: A 38-year-old patient was admitted with a diagnosis of alcohol-induced acute pancreatitis and managed conservatively.
Coinfection of and Other Microorganisms: A Systematic Review and Meta-Analysis.
Microorganisms
October 2024
Escuela de Biología, Universidad Autónoma de Sinaloa, Culiacán 80050, Sinaloa, Mexico.
Toxoplasmosis is a disease caused by the intracellular protozoan , which has infected a third of the global population. Immunocompromised individuals and children with congenital disorders are most likely to be impacted by toxoplasmosis, and accurate diagnosis is essential. Toxoplasmosis is associated with HIV, schizophrenia, and diabetes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!