Conflicts between transcription and replication are a major source of replication stress. Our recent findings show that proper dephosphorylation of Serine 5 in the carboxy-terminal domain (CTD) of DNA-directed RNA polymerase II subunit RPB1 is needed to prevent such conflicts in human cells.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128203 | PMC |
| http://dx.doi.org/10.1080/23723556.2021.1910008 | DOI Listing |
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