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| http://dx.doi.org/10.1016/j.jdcr.2021.03.043 | DOI Listing |
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Resolution of Bullous Pemphigoid Following Lung Cancer Resection: A Case of Paraneoplastic Pemphigoid.
Cureus
November 2024
Department of Dermatology, JR Sapporo Hospital, Sapporo, JPN.
Bullous pemphigoid (BP) is a chronic autoimmune disorder characterized by subepidermal blister formation, primarily affecting elderly individuals. While BP has been associated with malignancies, the exact nature of this relationship remains unclear. We report the case of a 72-year-old man who presented with pruritic cutaneous lesions, including tense vesicles and bullae and was diagnosed with BP.
View Article and Find Full Text PDFUse of multivariant enzyme-linked immunosorbent assay (ELISA) in the diagnosis of autoimmune bullous disorders in a resource-limited setting: A single-center experience.
Indian J Dermatol Venereol Leprol
November 2024
Department of Dermatology, Venerology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Article Synopsis
- Autoimmune blistering disorders (AIBD) are conditions where the body produces auto-antibodies against adhesion proteins in the skin, detectable through direct immunofluorescence (DIF) or blood tests like ELISA.
- This study aimed to assess how well the results from a new multivariant ELISA method agreed with AIBD diagnoses established from clinical assessments, histopathology, and DIF.
- The results showed a good overall correlation between ELISA and diagnoses, particularly strong in pemphigus vulgaris, but with variable agreement levels in other types of AIBD and limitations due to the retrospective nature of the study.
[Autoimmune blistering dermatosis as a paraneoplastic syndrome secondary to testicular cancer].
Rev Med Inst Mex Seguro Soc
July 2024
Instituto Mexicano del Seguro Social, Hospital General de Zona No. 47, Servicio de Medicina Interna, Ciudad de México, México.
Article Synopsis
The use of ibrutinib for the management of paraneoplastic bullous pemphigoid associated with monoclonal B-lymphocytosis: A case report and brief literature review.
JAAD Case Rep
November 2024
Dermatology Department, Scripps Health, San Diego, California.
A systematic review of paraneoplastic pemphigus and paraneoplastic autoimmune multiorgan syndrome: Clinical features and prognostic factors.
J Am Acad Dermatol
October 2024
Department of Dermatology and Venereology, West China Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address:
Article Synopsis
- Paraneoplastic pemphigus (PNP), also referred to as paraneoplastic autoimmune multiorgan syndrome (PAMS), is a rare and serious autoimmune condition affecting the skin, mucous membranes, and various organs, with a high risk of mortality.
- Researchers conducted a comprehensive analysis of 290 articles, including data from 504 patients, to gather insights on demographics, symptoms, associated tumors, treatment options, and survival outcomes.
- Key findings indicated that older age, specific autoantibodies, and non-Hodgkin lymphoma were linked to shorter survival, while initial oral mucosal involvement and certain skin conditions were associated with longer survival; the study highlighted significant prognostic factors for PNP/PAMS patients.
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