"Spontaneous" heparin-induced thrombocytopenia is a rare and virulent form of heparin-induced thrombocytopenia that occurs in the absence of exposure to any drug of the heparin class of anticoagulants. Most reported cases have occurred after knee replacement surgery. Herein we report 2 additional cases following total knee replacement. Clinical suspicion and immediate initiation of appropriate nonheparin anticoagulation are essential to avoid potentially devastating thrombotic complications.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121995 | PMC |
| http://dx.doi.org/10.1016/j.artd.2021.03.005 | DOI Listing |
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