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Effects of microbial fermentation on the anti-inflammatory activity of Chinese yam polysaccharides.
Front Nutr
January 2025
College of Tobacco Science and Engineering, Zhengzhou University of Light Industry, Zhengzhou, China.
In this study, Chinese yam polysaccharides (CYPs) were fermented using M616, and changes in the chemical composition, structure, and anti-inflammatory activity of CYPs before and after fermentation were investigated. The carbohydrate content of M616-fermented CYP (CYP-LP) increased from 71.03% ± 2.
View Article and Find Full Text PDFPediatric autoimmune neuropsychiatric disorders associated with streptococcal infections and gut microbiota composition: what do we know?
Front Nutr
January 2025
Department of Pediatrics, Vittore Buzzi Children's Hospital, University of Milan, Milan, Italy.
Post-streptococcal autoimmune neuropsychiatric disorders (PANDAS) are a group of pathological condition characterized by sudden-onset obsessive-compulsive and tic disorders following beta-hemolytic Streptococcus group A (GAS) infection, hypothesized to be caused by autoimmune mechanisms targeting the basal ganglia. Scant literature is available regarding the microbiota composition in children with PANDAS, however few studies support the hypothesis that streptococcal infections may alter gut microbiota composition in these patients, leading to chronic inflammation that may impact the brain function and behavior. Notable changes include reduced microbial diversity and shifts in bacterial populations, which affect metabolic functions crucial for neuroinflammation.
View Article and Find Full Text PDFThe interplay between gut microbiota composition and dementia.
Rev Neurosci
January 2025
Universal Scientific Education and Research Network (USERN), Tehran, 1416634793, Iran.
Recently, researchers have been interested in the potential connection between gut microbiota composition and various neuropsychological disorders. Dementia significantly affects the socioeconomics of families. Gut microbiota is considered as a probable factor in its pathogenesis.
View Article and Find Full Text PDFIntestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface.
Cardiovasc Res
January 2025
Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
Aims: The gastrointestinal (GI) tract is composed of distinct sub-regions, which exhibit segment-specific differences in microbial colonization and (patho)physiological characteristics. Gut microbes can be collectively considered as an active endocrine organ. Microbes produce metabolites, which can be taken up by the host and can actively communicate with the immune cells in the gut lamina propria with consequences for cardiovascular health.
View Article and Find Full Text PDF4-O-Methylglucuronoxylan from Hygrophila Ringens var. Ringens Seeds: Chemical Composition and Anti-Inflammatory Activity.
Macromol Biosci
January 2025
Friedrich Schiller University Jena, Institute for Organic Chemistry and Macromolecular Chemistry, Center of Excellence for Polysaccharide Research, Humboldtstraße 10, D-07743, Jena, Germany.
Hygrophila ringens var. ringens is a medicinal plant of the Acanthaceae family. A soluble polysaccharide is extracted from H.
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